Yusuf Azeez Olanrewaju, Surajudeen Monsurat Bolanle, Akinyemi Bolanle Temitope
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Common Plant Bioactive Components Adopted in Combating Gastrointestinal Nematodes in Small Ruminant – A Review
The high cost incurred by rural farmers on chemical anthelmintics, the reduction of the efficacy of this class of drugs and the development of resistant strains of Helminth has necessitate the search for suitable alternatives. However, there are still research gaps in the use plant secondary metabolites with no proper documentation of the active compound(s), standard administration route, mode of action, and standardization of its use in small ruminant animals. This review focuses on the use of bioactive components of plants and plant extracts in combating gastrointestinal nematodes (GIN) in ruminant animals. It highlights the importance of the use of plants in both ruminant nutrition and health, the flaws of conventional methods of treatment and the need for suitable alternatives. It further documents the major bioactive components of plants used in the treatment of GIN in ruminants and their mode of action on nematodes’ eggs, larva and adult worms. It is very clear that there exists a gap in research to validate the in vitro testing of some useful compounds in vivo owing to the identification of active components as most of them work in synergism with others, the dosing of the extracts is not uniform as the molecular weight of the selected compounds differs in most cases. Hence, this informs the need for collaborative research to validate the use of bioactive compounds and subsequent drug development to replace costly conventional anthelmintic that are constantly losing efficacy.
中国农业科学Agricultural and Biological Sciences-Agricultural and Biological Sciences (all)
CiteScore
1.90
自引率
0.00%
发文量
17516
期刊介绍:
Scientia Agricultura Sinica seeks to publish those papers that are influential and will significantly advance scientific understanding in agriculture fields worldwide. Scientia Agricultura Sinica publishes manuscripts in the categories focusing on the core subjects listed below. -Review describes new development and highlight future directions of a specialized or interdisciplinary significance in agricultural sciences. They should be focused on providing insights and summary/context on the published findings and introducing new concepts or viewpoints for solving the important unresolved questions by presenting the research background, approach, and outlook of the field. Most Reviews are solicited by the editors, but unsolicited submissions may also be considered. -Research Article presents important new research results through reproducible experimental design, using genetic, biochemical, cell and molecular biological methods, statistical analyses, and other scientific methods. -Research Notes is for a concise, but independent report representing a significant contribution to agricultural sciences. It is intended to publish these results that are exceptional interest and particularly topical and relevant, but the preliminary results. Core Subjects: -Crop Genetics & Breeding·GermplasmResources·Molecular Genetics -Tillage & Cultivation·Physiology & Biochemistry -Plant Protection -Soil & Fertilizer·Water-Saving Irrigation·Agro-Ecology & Environment -Horticulture -Storage·Fresh-Keeping·Processing -Animal Science·Veterinary Science -Agricultural Ecology -Research Notes