接受抗逆转录病毒治疗的艾滋病毒感染者的生活质量:突尼斯莫纳斯提尔的一项横断面研究

IF 1.5 Q4 INFECTIOUS DISEASES

HIV AIDS-Research and Palliative Care Pub Date : 2023-11-01 DOI:10.2147/hiv.s430376

Latifa Berrezouga, Ikbel Kooli, Wafa Marrakchi, Ghaya Harzallah, Mohamed Chakroun

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引用次数: 0

摘要

导语:尽管有效的抗逆转录病毒治疗(ART)带来了好处，但艾滋病毒/艾滋病的流行仍然是世界范围内对人们生活质量(QoL)产生负面影响的最严重的影响。由于突尼斯没有关于生活质量的研究，本研究的目的是:基于WHOQOL-HIV BREF工具，评估接受抗逆转录病毒治疗的艾滋病毒感染者(PLHIV)对生活质量的看法;以及ii:调查社会人口统计学特征、疾病相关变量与生活质量域平均得分之间的关系。方法:本横断面研究在突尼斯莫纳斯提尔F. Bourguiba教学医院传染病科进行。105名接受抗逆转录病毒治疗的参与者参与其中。生活质量评价依据WHOQOL-HIV概要，包括6个领域29个项目，得分从最低(4分)到最高(20分)不等。结果以频率和平均值(±SD)报告。采用独立样本的学生t检验和单因素方差分析来评估生活质量平均得分的差异。采用线性回归分析探讨影响生活质量的因素。置信区间设为95%。结果:患者平均年龄39.20±10.18岁，男女性别比3.12。环境(12.34±2.90)、社会关系(12.58±3.94)、心理(12.76±3.31)三个领域平均得分较低，身体(14.11±3.52)、精神(14.05±3.78)、独立水平(13.98±3.57)三个领域平均得分中等。回归分析显示，健康状况和感觉健康与生活质量各领域相关，职业、婚姻状况和自信与环境和精神领域相关。结论:抗逆转录病毒治疗影响hiv患者的生活质量。卫生保健利益攸关方应采取具体措施和战略，改善生活质量的决定因素。关键词:艾滋病毒感染者，WHO生活质量，突尼斯

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Quality of Life of People Living with HIV on Antiretroviral Therapy: A Cross-Sectional Study in Monastir, Tunisia

Introduction: Despite the benefits of an efficient antiretroviral therapy (ART), HIV/AIDS epidemic still represents the most seriousaffection worldwide that negatively impacts people’s quality of life (QoL). As no studies exist on QoL in Tunisia, the aim of the present work was i: to assess, based on WHOQOL-HIV BREF tool, the perception of QoL of people living with HIV (PLHIV) receiving ART and ii: to investigate the relationship between socio-demographic features, disease-related variables and QoL domains’ mean scores. Methods: This cross-sectional study was conducted at the department of infectious diseases of F. Bourguiba Teaching Hospital in Monastir, Tunisia. One hundred and five participants receiving ART were involved. QoL assessment was based on the WHOQOL-HIV Bref including six domains with 29 items with scores ranged from the lowest (4) to the highest (20). Results were reported as frequencies and means (±SD). The Student’s t -test for independent samples and the one-way ANOVA were performed to assess differences in QoL mean scores. Linear regression analysis was used to investigate predictors of QoL. The confidence interval was set at 95%. Results: Clients’ mean age was 39.20± 10.18 years old with a male to female sex ratio of 3.12. Low mean scores were seen with the environment (12.34± 2.90), social relations (12.58± 3.94) and psychological domains (12.76± 3.31), and moderate mean scores were noted for the physical (14.11± 3.52), the spiritual (14.05± 3.78) and the level of independence (13.98± 3.57) domains. Regression analysis showed that health status and feeling healthy were related to all QoL domains and that profession, marital status and the presence of a confident person were related to environment and spiritual domains. Conclusion: QoL of PLHIV on ART is affected. Concrete measures and strategies should be undertaken by healthcare stakeholders to improve QoL determinants. Keywords: people living with HIV, WHO quality of life, Tunisia

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来源期刊

HIV AIDS-Research and Palliative Care INFECTIOUS DISEASES-

CiteScore

3.00

自引率

6.70%

发文量

审稿时长

16 weeks

期刊介绍： About Dove Medical Press Dove Medical Press Ltd is part of Taylor & Francis Group, the Academic Publishing Division of Informa PLC. We specialize in the publication of Open Access peer-reviewed journals across the broad spectrum of science, technology and especially medicine. Dove Medical Press was founded in 2003 with the objective of combining the highest editorial standards with the ''best of breed'' new publishing technologies. We have offices in Manchester and London in the United Kingdom, representatives in Princeton, New Jersey in the United States, and our editorial offices are in Auckland, New Zealand. Dr Scott Fraser is our Medical Director based in the UK. He has been in full time clinical practice for over 20 years as well as having an active research interest.