Structural Relationship of Psychiatric Disorders, Quality of Life, Coping Styles and Their Associated Factors Among Brain Pathology Patients and Hematological Cancer Patients

Introduction: The study aimed to examine the structural relationship of major depressive disorder (MDD), anxiety disorder, various mental diseases, quality of life, coping methods, and other variables in patient with brain pathology and hematological cancer patients. Methods: A total of (n=215) samples were included in the structural equation modeling (SEM) analyses. The analyses were done with brain pathology patients (110) and haematological cancer patients (105). Results: In the current study, the multivariate normality kurtosis was 9.112 with c.r = 3.950 obtained in this SEM model. In the SEM model, the global health status towards MDD can explain about 30% of the variance. The global health status score was found to have a significant positive association with self-distraction coping styles, gender, and emotional functioning. Gender has a significant positive association with global health status, indicating that male patients have improved overall health. In terms of severity of MDD the positive correlation was found with panic disorder life time. Emotional functioning, self distraction and global health status were shown to have a significant and inverse relationship with the severity of MDD (p<0.05). Conclusion: The severity of MDD was found to have a strong and detrimental association with cancer types indicating the brain pathology patients tends to have more severity of depression compared to haematological cancer patients.