冠状动脉旁路移植术患者颈动脉疾病的流行病学方面:一项横断面研究

Mehran Dastanpoor, Arsalan Khaledifar, Mathias Hossein Aazami, Elham Raeisi, Abdolmajid Taheri
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引用次数: 0

摘要

背景和目的:冠状动脉手术重建术患者并发颈动脉疾病(CaAD)是围手术期卒中的重要危险因素。目前的研究探讨了冠状动脉外科血运重建术中心患者合并CaAD的流行病学特征。方法:本描述性分析横断面研究对在同一中心接受彩色双超声(CDS)问诊的所有冠状动脉手术重建术患者进行了为期两年的研究。从患者的医疗记录中收集人口统计学、临床、超声心动图、冠状动脉造影和彩色双超声数据。定量和定性数据分别用均值和标准差、数字和百分比表示。定量变量与定性变量之间的关系分别采用Pearson相关检验和卡方检验。结果:共纳入430例患者,平均年龄66.3±9.9岁,其中女性占35%。82%的患者术前行CDS;其中29%出现内膜-中膜比例增高,51%出现CtAD。结果显示,单侧受累77例,双侧受累143例。严重颈动脉狭窄占4%。年龄大于65岁(P=0.02)、不稳定型心绞痛(P=0.045)和冠状动脉闭塞(P=0.002)与CtAD的存在相关。最后,左右颈动脉狭窄的严重程度与糖尿病相关(P<0.05)。结论:冠状动脉手术重建术患者并发CtAD的发生率仍然很高。目前的资料提示术前常规行CDS的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Epidemiological Aspects of the Carotid Artery Disease in Patients Undergoing Coronary Artery Bypass Grafting: A Cross-sectional Study
Background and aims: Concomitant carotid artery disease (CaAD) in patients referred to coronary surgical revascularization is a strong hazard to perioperative stroke. The current study addressed the epidemiology features of concomitant CaAD in patients referred to a coronary surgical revascularization center. Methods: This descriptive-analytical cross-sectional study was conducted on all incoming patients to coronary surgical revascularization for two years at a single center who underwent a color duplex-sonography (CDS) interrogation. The demographic, clinical, echocardiographic, coronary angiographic, and color duplex-sonographic data were collected from patients’ medical records. Quantitative and qualitative data were expressed as means and standard deviations, as well as numbers and percentages, respectively. The relationships between quantitative and qualitative variables were investigated using Pearson’s correlation and chi-square test, respectively. Results: In total, 430 patients with a mean age of 66.3±9.9 years were included (35% females) in the study. Preoperative CDS was performed on 82% of patients; in addition, 29% of them presented with an increased intima-media ratio, and CtAD was observed in 51%. Based on the results, 77 and 143 patients were detected with unilateral and bilateral involvement, respectively. Severe carotid stenosis accounted for 4% of patients. Age older than 65 years (P=0.02), unstable angina (P=0.045), and the presence of an occluded coronary artery (P=0.002) were associated with the presence of CtAD. Finally, the severity of the left and right carotid stenosis was associated with diabetes mellitus (P<0.05). Conclusion: The prevalence of concomitant CtAD in patients referred to coronary surgical revascularization remains high. The current data warn of the necessity of performing preoperative CDS routinely.
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