喀麦隆雅温得一家三级医院2型糖尿病大血管并发症的患病率及相关因素

IF 0.7 Q4 ENDOCRINOLOGY & METABOLISM
Francine Mendane Ekobena, Martine Claude Etoa Etoga, Mesmin Dehayem, Carole Laurence Ngo Yon, Pauline Ngo Balôgôg, Guy Dieudonné Mvogo, André Pascal Kengne, Eugène Sobngwi, Jean Claude Mbanya
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引用次数: 0

摘要

2型糖尿病(T2D)诊断时出现血管并发症是发展中国家的一个沉重负担。我们的目的是确定大血管并发症的患病率和相关的T2D诊断在喀麦隆雅温得。材料与方法:我们于2017年1月至2021年6月在雅温得埃索斯医院中心进行了一项横断面研究。我们招募了新诊断为T2D的患者,同时评估了大血管并发症,包括卒中、心肌梗死(MI)和动脉性足溃疡(AFU)。使用卡方检验和逻辑回归研究相关因素。显著性水平设为5%。结果:共纳入286例新诊断糖尿病患者,其中男性占51.7%。平均年龄52.6±12.3岁。糖尿病诊断时常见的心血管危险因素是血脂异常(63.6%)、久坐不动的生活方式(57.7%)和2型糖尿病家族史(51.6%)。大血管并发症发生率为17.5%,其中脑卒中8.4%,心肌梗死5.6%,动脉性足溃疡3.4%。高血压与所有大血管并发症相关(p < 0.05)。高糖化血红蛋白和年龄≥50岁与卒中相关,吸烟和肥胖分别与心梗和AFU相关。结论:在我们的研究中,大血管并发症在2型糖尿病诊断中较为常见,以卒中和心肌梗死为代表,这凸显了糖尿病患者从诊断开始就进行心血管风险评估和降低风险的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence and Correlates of Macrovascular Complications at Type 2 Diabetes Diagnosis in a Tertiary Hospital in Yaound&#233;, Cameroon
Introduction: The presence of vascular complications at type 2 diabetes (T2D) diagnosis is a heavy burden for developing countries. We aimed to determine the prevalence and correlates of macrovascular complications at T2D diagnosis in Yaoundé, Cameroon. Materials and Methods: We conducted a cross-sectional study at the Essos Hospital Center in Yaoundé from January 2017 to June 2021. We recruited patients newly diagnosed with T2D who, simultaneously, with assessed macrovascular complications including stroke, myocardial infarction (MI) and arterial foot ulcer (AFU). Correlates were investigated using Chi square test and logistic regressions. The significance level was set at 5%. Results: In all, 286 newly diagnosed diabetic patients (51.7% being men) were included. The mean age was 52.6 ± 12.3 years. Prevalent cardiovascular risk factors at diabetes diagnosis were a dyslipidemia (63.6%), sedentary lifestyle (57.7%) and family history of type 2 diabetes (51.6%). The prevalence of macrovascular complications was 17.5% with 8.4% stroke, 5.6% myocardial infarction and 3.4% arterial foot ulcer. Hypertension was associated with all macrovascular complications (p < 0.05). High glycated hemoglobin and age ≥ 50 years were associated with stroke while tobacco and obesity were associated with MI and AFU respectively. Conclusion: Macrovascular complications are frequent at type 2 diabetes diagnosis and are represented by stroke and myocardial infarction in our study, highlighting the importance of cardiovascular risk evaluation and reduction in people with diabetes right from diagnosis.
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来源期刊
Diabetes Mellitus
Diabetes Mellitus ENDOCRINOLOGY & METABOLISM-
CiteScore
1.90
自引率
40.00%
发文量
61
审稿时长
7 weeks
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