K. T. Erimbetov, R. A. Zemlyanoy, A. V. Fedorova, O. V. Obvintseva
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Experimental Model to Substantiate the Application of New Biologically Active Substances for Correcting Physiological Processes and Functions
In this research, we aim to develop and investigate nanostructured clathrate complexes of 20-hydroxyecdysterone, a rhodanine derivative of 3-(2-phenylethyl)-2-thioxo-1,3-thiazolidin-4-one, with various clathrate formers, such as arabinogalactan and β-cyclodextrin. For the first time, an experimental model is proposed to justify their use for the correction of physiological processes and functions, both in normal and pathologic conditions in the animal body. The results obtained substantiate the possibility of regulating metabolic processes by activating signaling pathways associated with cell proliferation.
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