恒河猴同种异体免疫预防管理:以宾格维尔/科特迪瓦/西非多米尼克·瓦塔拉母婴医院为例

Ana Touré Ecra, Luc Olou, Perel Konan
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引用次数: 0

摘要

与许多发展中国家一样,Côte科特迪瓦与胎儿红细胞异体免疫引起的胎儿贫血相关的围产期死亡率可以通过缺乏对恒河猴d胎母异体免疫的了解来解释,因此开展一项关于预防恒河猴阴性出生的异体免疫问题的研究具有明显的重要性。本研究评估了一家参考医院对这种病理的处理。结果和讨论:rh阴性母亲占分娩的6%,42.7%(70/164)的妇女有风险史,约61%的妇女在以前的怀孕期间没有采取适当的预防措施;由于许多人在怀孕期间没有进行库姆斯测试的后续检查;只有4.9%的患者在妊娠28周时进行了系统的抗D血清预防。这种低预防率与患者的经济困难有关,但也与护理人员缺乏病理知识有关。结论:对恒河阴性妇女妊娠期间的良好管理,使其不相容的孩子受益于目前所有的治疗,确保健康出生。因此,对于医务人员来说,了解如何在一小部分孕妇中处理这种罕见疾病是很重要的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Management of the Prevention of the Rhesus Alloimmunization: Case of the Mother-Child Hospital Dominique Ouattara of Bingerville/Ivory Coast/West Africa
Introduction: Perinatal mortality linked to fetal anemia of red cell alloimmunization in Côte d’Ivoire as in many developing countries can be explained by a lack of knowledge of Rhesus D feto-maternal alloimmunization, hence the obvious importance of carrying out a study on the problem of prevention of alloimmunization in rhesus negative births. This study takes stock of the management of this pathology in a reference hospital. Results and Discussion: Rh-negative mothers account for 6% of births, 42.7% (70/164) of women had a history of risk, about 61% of women had not had proper prophylaxis during previous pregnancies; and as many had not had follow-up of the coombs test during the current pregnancy; only 4.9% of patients had systematic prophylaxis with anti D serum at 28 weeks of pregnancy. This low rate of prevention is related to the financial difficulties of the patients, but also to a lack of knowledge of the pathology by the nursing staff. Conclusion: Good management of rhesus negative women during their pregnancy allows their incompatible child to benefit from all current treatments ensuring a healthy birth. It is therefore important for medical personnel to know how to deal with this rare disease in a small proportion of pregnant women.
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