全麻后神经炎症与血脑屏障衰弱的关系

Dr. Nitin Kumar Sachdeva
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引用次数: 0

摘要

医学的最新进展使得通过外科手术成功治疗许多疾病成为可能,这些手术通常需要使用全身麻醉。人们对与麻醉剂相关的中枢神经系统(CNS)问题越来越感兴趣,随着全身麻醉剂的使用越来越普遍,对其安全性的担忧也在上升。近年来,大量研究指出,麻醉后出现的中枢神经系统问题与血脑屏障(BBB)功能障碍和神经炎症有关。需要更多的研究来确定全身麻醉是否会导致血脑屏障衰竭和神经炎症,以及这种相互作用是否可能是治疗中枢神经系统问题的一种选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Relationship between neurological inflammation and debilitated blood brain barrier subsequent to General Anaesthesia
Recent advances in medicine have made it possible to successfully treat numerous disorders through surgical procedures, which frequently need the use of general anaesthetic. There is a rising interest in the CNS (central nervous system) issues related to anaesthetics, and concerns about the safety of general anaesthetic are on the rise as their usage becomes more commonplace. Recent years have seen a wealth of research pointing to the involvement of blood-brain-barrier (BBB) dysfunction and neurological inflammation in the emergence of CNS problems in the wake of anaesthesia. More research is needed to determine whether or not general anaesthesia causes BBB failure and neuroinflammation, and whether or not this interaction might be an option for treatment for CNS problems.
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