PO98

Purpose Development of brachytherapy template as a radiation treatment guidance device to localize deep seated tumors. Materials and Methods The template of specific size and dimension were designed using solid modeling computer-aided design (Solid Works, Dassault systemes). The design was further converted to 3D printing readable format (. stl format). All the parts of the design were printed in 3D printer (Phrozen Technology, Taiwan) using stereolithography technology (SLA). A resin material in liquid form was laid on the 3D printer platform for printing. Lifting speed of the printing plate was set at 40 mm/min. The retract speed was 150 mm/min. The exposure time was set at 3.5 s. The newly designed template with all accessories were scanned in an X-ray CT scanner for imaging compatibility purpose. Scanning parameters were as follows: Tube Voltage - 120 kV, slice thickness - 2.0 mm, Tube Current - 305 mA, pixel size - 0.6738 x 0.7638 mm2 and etc. Results The overall process took 3 hours to print the design with printing resolution of 50 microns. Various parts of the design were produced in a layer-by-layer fashion. By photochemical process, the chosen resin material cross-linked together to form polymers. In the imaging study the Hounsfield unit (HU) value of the resin material for template design was found to be 250 HU. The newly printed template had angled holes around 80 degrees to insert and maneuver interstitial needles. The template design was built in such a way that obturators, rectal probe and related accessories were easily positioned and immobilized in the template capable of tumor localization in real clinical situation. A rectal probe was built as well with the base template. Conclusions We are further developing a human pelvis phantom to test the efficacy of the new 3D printed template which we will show in our future studies. The ultimate goal of this study is to personalize patient treatment with an affordable and cost-effective solution. The newly designed template is capable of performing brachytherapy procedure. Further dosimetric validation study is required to explore the potential of the template for clinical use purpose. Development of brachytherapy template as a radiation treatment guidance device to localize deep seated tumors. The template of specific size and dimension were designed using solid modeling computer-aided design (Solid Works, Dassault systemes). The design was further converted to 3D printing readable format (. stl format). All the parts of the design were printed in 3D printer (Phrozen Technology, Taiwan) using stereolithography technology (SLA). A resin material in liquid form was laid on the 3D printer platform for printing. Lifting speed of the printing plate was set at 40 mm/min. The retract speed was 150 mm/min. The exposure time was set at 3.5 s. The newly designed template with all accessories were scanned in an X-ray CT scanner for imaging compatibility purpose. Scanning parameters were as follows: Tube Voltage - 120 kV, slice thickness - 2.0 mm, Tube Current - 305 mA, pixel size - 0.6738 x 0.7638 mm2 and etc. The overall process took 3 hours to print the design with printing resolution of 50 microns. Various parts of the design were produced in a layer-by-layer fashion. By photochemical process, the chosen resin material cross-linked together to form polymers. In the imaging study the Hounsfield unit (HU) value of the resin material for template design was found to be 250 HU. The newly printed template had angled holes around 80 degrees to insert and maneuver interstitial needles. The template design was built in such a way that obturators, rectal probe and related accessories were easily positioned and immobilized in the template capable of tumor localization in real clinical situation. A rectal probe was built as well with the base template. We are further developing a human pelvis phantom to test the efficacy of the new 3D printed template which we will show in our future studies. The ultimate goal of this study is to personalize patient treatment with an affordable and cost-effective solution. The newly designed template is capable of performing brachytherapy procedure. Further dosimetric validation study is required to explore the potential of the template for clinical use purpose.