Letícia Prieto Trindade, Alessandra Vidal Prieto, Rafael Marcos Dias Costa, Michelly Rodrigues Cavalcante, Inácio Carlos Murta Júnior, Renata Nunes Lima, Lorrane Azevêdo De Souza, Fábio Ferreira Amorim, Dilson Palhares Ferreira
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引用次数: 0
摘要
骨骼肌减少症是一种进行性和广泛性骨骼肌疾病,具有多因素和复杂的病因。它涉及骨骼肌质量的加速损失,并与老年人的负面结果增加有关,如功能下降、虚弱、跌倒和死亡。目的:探讨老年人肌肉减少症与跌倒和死亡风险的关系。方法:对文献进行系统综述,考虑到观察性文章的出版分类纳入。符合条件的研究是在PubMed、Web of Science、EMBASE和LILACS数据库中搜索的结果。描述符用于搜索。还包括由DECS提供的葡萄牙语和西班牙语相同的描述符(健康科学描述符)。结果:922篇入选文献中,14篇被纳入综述。大多数研究的结果都是相似的:肌肉减少症与跌倒风险之间存在正相关关系(p <0.0001),老年人群肌肉减少症和死亡率(p = 0.009)。结论:骨骼肌减少症是老年人跌倒和死亡率增高的危险因素。
CORRELATION BETWEEN SARCOPENIA, RISK OF FALLS AND MORTALITY IN THE ELDERLY - SYSTEMATIC REVIEW AND META-ANALYSIS OF OBSERVATIONAL STUDIES
Introduction: Sarcopenia is a progressive and generalized disorder of the skeletal muscles with multifactorial and complex causes. It involves an accelerated loss of skeletal muscle mass and is associated with increased negative outcomes in older adults, such as functional decline, frailty, falls, and death. Objective: to correlate sarcopenia with the risk of falls and mortality in the elderly. Method: A systematic review of the literature was carried out, considering the publication of observational articles as classified for inclusion. The studies considered eligible were the results of searches in the PubMed, Web of Science, EMBASE and LILACS databases. The descriptors were used for searching. The same descriptors in Portuguese and Spanish provided by DECS (health sciences descriptors) were also included. Results: Of the 922 articles selected, 14 were included in the review. The results were similar in most of the articles identified: there is a positive manifestation between sarcopenia, risk of falls (p < 0.0001) and sarcopenia and mortality (p = 0.009) in the elderly population. Conclusion: It is concluded that sarcopenia is a risk factor for falls and increased general mortality in the elderly.