开发苯甲酰基苯基脲及其关键中间体的新制造路线

IF 2.4 3区化学 Q2 CHEMISTRY, ORGANIC

Polycyclic Aromatic Compounds Pub Date : 2024-10-20 DOI:10.1080/10406638.2023.2272013

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引用次数: 0

摘要

本研究揭示了一种新的高效生产技术，用于制备苯甲酰苯基脲及其关键中间体。这条新路线将反应步骤从六个大幅减少到三个，从而简化了工艺流程。此外，总产率从 56% 提高到 69% 以上。与原来的工艺路线相比，新的生产路线具有化学步骤更少、总收率更高、工艺安全隐患更少以及对环境影响更小等优点。考虑到这些因素，新的生产工艺路线具有相当大的工业化潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Development of a New Manufacturing Route for Benzoylphenylureas and Their Key Intermediates

A new and efficient manufacturing technology is disclosed in the present work for the preparation of benzoylphenylureas and their key intermediates. This new route significantly reduces the number of reaction steps from six to three, resulting in a streamlined process. Additionally, the overall yield is increased from 56% to over 69%. Compared to the original process route, the new manufacturing route has the advantages of fewer chemical steps, higher overall yield, less process safety hazard and environmental impact. Considering these factors, the new manufacturing route exhibits considerable potential for industrialization.

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来源期刊

Polycyclic Aromatic Compounds 化学-有机化学

CiteScore

3.70

自引率

20.80%

发文量

412

审稿时长

3 months

期刊介绍： The purpose of Polycyclic Aromatic Compounds is to provide an international and interdisciplinary forum for all aspects of research related to polycyclic aromatic compounds (PAC). Topics range from fundamental research in chemistry (including synthetic and theoretical chemistry) and physics (including astrophysics), as well as thermodynamics, spectroscopy, analytical methods, and biology to applied studies in environmental science, biochemistry, toxicology, and industry. Polycyclic Aromatic Compounds has an outstanding Editorial Board and offers a rapid and efficient peer review process, as well as a flexible open access policy.