精神科执业药师对提高急性精神病院尿路感染抗生素适宜性的影响

Mohammad Adam Hamad, Andrew Williams, Jamie Kneebusch, Niyati Butala
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引用次数: 0

摘要

摘要导读尿路感染(uti)是抗生素使用最常见的适应症之一;与没有精神障碍的患者相比,有精神障碍的患者患尿路感染的风险更大。然而,在精神病院如何最好地管理抗生素治疗方面,几乎没有指导。本研究评估了委员会认证精神科药剂师(BCPP)驱动的指南对急性精神病院尿路感染治疗管理的影响。方法由精神科药学小组编制指南,分发给内科医生、精神科医生和药师。评估2019年11月30日至2020年2月23日期间入院患者的干预前数据;评估2020年2月25日至2020年4月24日的干预后数据。所有年龄在13岁及以上、入院并接受抗生素治疗尿路感染的患者都被纳入本研究。适当的尿路感染管理被定义为根据治疗指南使用适当的药物、剂量、途径和频率。此外,以下标准将被订购并评估为适当:尿液分析、尿液培养、全血细胞计数、基本或完全代谢组、体温和主观症状。结果干预前,19.0%的抗菌药物处方合理;干预后,46.7%的抗生素订单是合适的(P = 0.048)。结论bcpp驱动的治疗算法的实施与精神病院住院患者治疗尿路感染的适当抗生素方案的显着增加有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Impact of Board Certified Psychiatric Pharmacists on improving urinary tract infection antibiotic appropriateness at an acute psychiatric hospital
Abstract Introduction Urinary tract infections (UTIs) are one of the most common indications for antibiotic use; patients with psychiatric disorders have a greater risk for UTI compared with patients without these disorders. However, there is little guidance on how best to manage antibiotic therapy in psychiatric hospitals. This study assessed the impact of a Board Certified Psychiatric Pharmacist (BCPP)–driven guideline on managing UTI treatment in an acute psychiatric hospital. Methods The guideline was developed by the psychiatric pharmacy team and distributed to internists, psychiatrists, and pharmacists. Preintervention data were assessed for patients admitted between November 30, 2019, and February 23, 2020; postintervention data were assessed from February 25, 2020, to April 24, 2020. All patients ages 13 years and older who were admitted and had orders for an antibiotic to treat a UTI were included in this study. Appropriate UTI management was defined as an appropriate agent, dose, route, and frequency per the treatment guideline. Additionally, the following criteria were to be ordered and assessed to be deemed appropriate: urinalysis, urine culture, complete blood count, basic or complete metabolic panel, temperature, and subjective symptoms. Results Before intervention, 19.0% of antibiotic orders were appropriate; after intervention, 46.7% of antibiotic orders were appropriate (P = .048). Conclusion The implementation of a BCPP-driven treatment algorithm was associated with a significant increase in appropriate antibiotic regimens for the treatment of UTIs in patients admitted to a psychiatric hospital.
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