n -乙酰半胱氨酸在临床中的意义

Q4 Medicine

Pulmonologiya Pub Date : 2023-09-05 DOI:10.18093/0869-0189-2023-33-5-679-688

I. V. Leshchenko, N. A. Esaulova

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引用次数: 0

摘要

n -乙酰半胱氨酸(NAC)是一种具有多种性能的解粘剂和抗氧化剂。NAC的临床应用已超过35年，在此期间，重点是多方面的作用和广泛的治疗适应症。有关NAC在预防造影剂肾病方面的疗效、NAC在治疗肺部和冠状动脉疾病方面的作用的研究等方面的信息。本综述旨在分析NAC在呼吸系统临床应用中的有效性和安全性。结论。NAC是一种具有多种独特特性和治疗选择的药物。该药物已在实际肺内科实践中证明了其有效性和安全性。

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Significance of N-acetylcysteine in clinical practice

N-acetylcysteine (NAC) is a mucolytic and antioxidant with a variety of properties. The clinical use of NAC spans more than 35 years, during which the emphasis has been on a multifaceted action and broad spectrum of therapeutic indications. Information is available on the efficacy of NAC in the prevention of contrast-induced nephropathy, studies on the role of NAC in the treatment of pulmonary and coronary disease, etc. The purpose of this review is to analyze the efficacy and safety of NAC in respiratory clinical practice. Conclusion. NAC is a drug with a unique variety of properties and treatment options. The drug has proven its efficacy and safety in real pulmonology practice.

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来源期刊

Pulmonologiya Medicine-Pulmonary and Respiratory Medicine

CiteScore

1.40

自引率

0.00%

发文量

期刊介绍： The aim of this journal is to state a scientific position of the Russian Respiratory Society (RRS) on diagnosis and treatment of respiratory diseases based on recent evidence-based clinical trial publications and international consensuses. The most important tasks of the journal are: -improvement proficiency qualifications of respiratory specialists; -education in pulmonology; -prompt publication of original studies on diagnosis and treatment of respiratory diseases; -sharing clinical experience and information about pulmonology service organization in different regions of Russia; -information on current protocols, standards and recommendations of international respiratory societies; -discussion and consequent publication Russian consensus documents and announcement of RRS activities; -publication and comments of regulatory documents of Russian Ministry of Health; -historical review of Russian pulmonology development. The scientific concept of the journal includes publication of current evidence-based studies on respiratory medicine and their discussion with the participation of Russian and foreign experts and development of national consensus documents on respiratory medicine. Russian and foreign respiratory specialists including pneumologists, TB specialists, thoracic surgeons, allergists, clinical immunologists, pediatricians, oncologists, physiologists, and therapeutists are invited to publish article in the journal.