c反应蛋白、白细胞及免疫球蛋白在婴幼儿肺炎急性期诊治中的临床应用

IF 1 4区医学 Q3 EMERGENCY MEDICINE

Signa Vitae Pub Date : 2023-01-01 DOI:10.22514/10.22514/sv.2023.089

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引用次数: 0

摘要

本研究旨在探讨c反应蛋白、白细胞及免疫球蛋白在婴幼儿肺炎急性期诊治中的临床意义。选择2018年1 - 12月我院收治的124例肺炎患儿和健康儿童作为研究对象。其中62名确诊为细菌性肺炎的儿童作为研究组，62名来体检的健康儿童作为对照组。观察并比较两组患者c反应蛋白(CRP)、白细胞(WBC)及免疫球蛋白(IgA、IgM、IgG)水平。本研究中，研究组CRP、IgM、IgG、WBC水平高于对照组，IgA水平低于对照组。研究组CRP、IgM、IgG、WBC水平较低，但轻度肺炎患儿IgA水平高于重症肺炎患儿。治疗后CRP、IgM、IgG、WBC水平较治疗前下降，IgA水平较治疗前升高。特别是研究组治疗后CRP、WBC、IgA、IgM、IgG水平均恢复到与对照组相当的水平。因此，c反应蛋白、白细胞和免疫球蛋白可用于判断儿童肺炎急性期的诊断、病情和转归。本研究可为临床指导婴幼儿肺炎的诊治提供依据

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Clinical application of C-reactive protein, leukocyte and immunoglobulin in the diagnosis and treatment of infantile pneumonia at acute stage

This study aims to explore the clinical significance of C-reactive protein, leukocyte and immunoglobulin in the diagnosis and treatment of infantile pneumonia at acute stage. From January to December 2018, a total of 124 children with pneumonia and healthy children admitted to our hospital were selected as study objects. Among them, 62 children diagnosed with bacterial pneumonia were categorized as the study group, and 62 healthy children who came for physical examination were classified as the control group. The levels of C-reactive protein (CRP), white blood cell (WBC) and immunoglobulin (IgA, IgM and IgG) were observed and compared in the two groups. In this study, higher levels of CRP, IgM, IgG and WBC, along with lower level of IgA were observed in the study group as compared with that in the control group. In the study group, the levels of CRP, IgM, IgG and WBC were lower, but the IgA level was higher in children with mild pneumonia than those with severe pneumonia. After treatment, the levels of CRP, IgM, IgG and WBC were decreased but IgA level was increased after treatment compared with before treatment. In particular, the levels of CRP, WBC, IgA, IgM and IgG in the study group after treatment were restored to comparable levels compared with the control group. Therefore, C-reactive protein, leukocyte and immunoglobulin can be used to determine the diagnosis, condition and outcome of children with pneumonia in the acute stage. This study can provide guidance for clinical diagnosis and treatment of infantile pneumonia based

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来源期刊

Signa Vitae 医学-急救医学

CiteScore

1.30

自引率

9.10%

发文量

审稿时长

3 months

期刊介绍： Signa Vitae is a completely open-access，peer-reviewed journal dedicate to deliver the leading edge research in anaesthesia, intensive care and emergency medicine to publics. The journal’s intention is to be practice-oriented, so we focus on the clinical practice and fundamental understanding of adult, pediatric and neonatal intensive care, as well as anesthesia and emergency medicine. Although Signa Vitae is primarily a clinical journal, we welcome submissions of basic science papers if the authors can demonstrate their clinical relevance. The Signa Vitae journal encourages scientists and academicians all around the world to share their original writings in the form of original research, review, mini-review, systematic review, short communication, case report, letter to the editor, commentary, rapid report, news and views, as well as meeting report. Full texts of all published articles, can be downloaded for free from our web site.