半现象学模型在猪辐射致肺病实验数据中的应用。

Radiobiologia, radiotherapia Pub Date : 1990-01-01
K Prokes, L Judas, M Lokajicek, T Herrmann, L Voigtmann
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引用次数: 0

摘要

一个半现象学模型被推导出来,用存活曲线描述了对单个细胞的失活效应。该模型适用于猪肺病的实验数据。计算并讨论了相应的生存曲线以及细胞生存与并发症概率的关系。此外,还推导了单剂量辐照和不同分级方案的剂量响应曲线。单剂量辐照的响应曲线与文献中类似曲线的比较表明,两者吻合较好。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Application of a semi-phenomenological model to experimental data of radiation induced pneumopathy in pigs.

A semi-phenomenological model has been derived, which describes the inactivation effect on individual cells by survival curves. This model is applied to experimental data of pneumopathy in pigs. The corresponding survival curves as well as the relations between cell survival and complication probability are calculated and discussed. Furthermore, dose-response curves for single dose irradiation and different fractionation schemes are derived. The comparison between the response curve for single dose irradiation and similar curves from the literature shows a good agreement.

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