显微镜下血尿作为钢铁工人泌尿系统疾病的预测指标。

B C Choi, J A Farmilo
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引用次数: 7

摘要

研究人员从1974年到1986年对加拿大安大略省一家钢铁厂的501名工人进行了为期13年的跟踪调查。结果表明,在随访期开始时(1974年)显微镜血尿分析阳性的工人中,13年泌尿系统疾病的累计发病率是尿检阴性工人的1.3倍(95%可信区间0.6-2.8)。在调整了年龄和吸烟因素后,这一相对风险保持不变。这表明,显微镜下血尿筛查可能是泌尿系统疾病发生的有用预测指标。然而,早期发现和管理的好处很难证明。在本研究中,严重的泌尿系统疾病,特别是泌尿系癌症,由于泌尿系筛查试验未能及早发现。过去已经进行了几项研究来验证该测试。建议做更多的工作来验证测试并确定预测的准确性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Microscopic haematuria as a predictor of urological diseases among steel workers.

A cohort of 501 workers in a steel mill in Ontario, Canada was followed up from 1974 to 1986 for 13 years. Results indicate that the 13-year cumulative incidence of urological diseases among workers who had a positive urinalysis result of microscopic haematuria at the beginning of the follow-up period (1974) was 1.3 times that of those who had a negative urinalysis result (95% confidence interval 0.6-2.8). This relative risk remained the same after adjusting for age and smoking. This indicates that there is a possibility that urinary screening for microscopic haematuria could be a useful predictor of urological disease occurrence. However, the benefits of early detection and management were difficult to demonstrate. Serious urological diseases, particularly urinary cancers, were not detected earlier as a result of the urinary screening test in this study. Several studies have been done to validate the test in the past. More work to validate the test and to determine the predictive accuracy is recommended.

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