酒精相关肝病和酒精相关肝炎的预后模型

IF 3.2 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY
Jessica Ann Musto, Michael Ronan Lucey
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引用次数: 0

摘要

酒精相关性肝病(ALD)和酒精相关性肝炎(AH)是动态疾病,其预后很难确定。已经开发了许多预后模型来确定死亡的可能性,何时进行肝移植(LT)以及糖皮质激素的作用。通常,这些模型是为特定的应用程序而创建的,但通过进一步研究发现它们具有其他应用程序。那些经受住时间考验的预测模型易于使用,有明确的解释,并采用客观参数。这些参数通常包括总胆红素、INR和肌酐等数据点。理想情况下,这些模型可以用于疾病的所有阶段,但在大多数情况下,临床医生考虑饮酒史及其如何改变确定的分数是很重要的。在此,我们简要回顾ALD和AH的预后模型,并提供实用的技巧和注意事项,以成功地在临床环境中使用这些工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prognostic models in alcohol-related liver disease and alcohol-related hepatitis

Alcohol-associated liver disease (ALD) and alcohol-associated hepatitis (AH) are dynamic disorders whose prognosis can be challenging to determine. A number of prognostic models have been developed to determine likelihood of death, when to refer for liver transplant (LT) and the role for glucocorticoids. Often these models were created with a specific application in mind but were found to have additional applications with further study. Those prognostic models that have stood the test of time are easy to use, have clear interpretations and employ objective parameters. These parameters most often include total bilirubin, INR and creatinine among other data points. Ideally, these models could be utilized at all phases of disease but in most, it is important for clinicians to consider drinking history and how it might alter the determined scores. Herein we provide a brief review of prognostic models in ALD and AH and provide practical tips and considerations to successfully make use of these tools in a clinical setting.

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来源期刊
CiteScore
5.50
自引率
0.00%
发文量
23
审稿时长
69 days
期刊介绍: Each topic-based issue of Best Practice & Research Clinical Gastroenterology will provide a comprehensive review of current clinical practice and thinking within the specialty of gastroenterology.
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