内镜鼻窦手术对慢性鼻窦炎合并鼻息肉患者生活质量的影响

Mustapha Sellami, Samira Abdi, Farid Boudjenah
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A SNOT-22 test was completed item by item with our patients, before any surgery, and after endoscopic sinus surgery at 1 month, 3 months, 6 months, 9 months, and 12 months. Results Sixty-five patients, having undergone ESS for CRS with nasal polyposis, were followed during a period 12 months. The average age of our patients was 42.06 ± 12.47 years, with 41.5% females and 58.5% males. Clinical examination showed that impairment was bilateral in 100% of our patients, while the nasal endoscopy showed that the polyps reached stage III in 87.7% of the cases on the right and 80% on the left. The mean Lund-Mackay CT score was 18.71 ± 4.77/24. All of the patients were treated with local and general short courses of corticosteroid therapy before ESS was indicated. Our results showed improvement in the QoL of our patients and maintenance of this gain after surgery. 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摘要

生活质量(QoL)测试通常用于评估对不同治疗的反应。它们是最能反映病人抱怨、病理严重程度和治疗后收获的工具。本研究的目的是评估内镜鼻窦手术(ESS)对慢性鼻窦炎合并鼻息肉(CRSwNP)患者生活质量(QoL)的影响,采用鼻结局测试22项(SNOT-22)。方法:本研究是一项前瞻性、描述性、单中心研究,纳入2017年1月1日至2019年12月31日在北海亚大学附属医院接受CRS合并鼻息肉手术治疗的所有患者,为期36个月。我们的患者在任何手术前和内窥镜鼻窦手术后的1个月、3个月、6个月、9个月和12个月逐项完成SNOT-22测试。结果对65例CRS合并鼻息肉患者行ESS治疗,随访12个月。患者平均年龄42.06±12.47岁,女性占41.5%,男性占58.5%。临床检查显示100%的患者为双侧损伤,鼻内镜检查显示右侧息肉达到III期的占87.7%,左侧息肉达到80%。lnd - mackay CT平均评分为18.71±4.77/24。所有患者在接受ESS前均接受局部和一般短期皮质类固醇治疗。我们的结果显示患者的生活质量得到改善,并在手术后保持了这种改善。术前平均SNOT-22总分为49.41±17.12;术后1个月为12.14±10.22;3个月后10.31±8.17;6个月后9.35±8.93;9个月后12.21±15.45,12个月后12.63±16.23。结论ESS是治疗药物治疗失败的慢性鼻窦炎鼻息肉病的金标准。使用SNOT-22测试使我们能够确认无论采用何种手术方法,术后生活质量都有所改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of endoscopic sinus surgery on quality of life among the patients of chronic rhinosinusitis with nasal polyposis
Abstract Background Quality of life (QoL) tests are usually used to assess the response to different therapies. They are the tools that best reflect the patients’ complaints, the severity of their pathology, and the post-therapeutic gains. The aim of the present study is to assess the effect of endoscopic sinus surgery (ESS) on quality of life (QoL) among the patients of chronic rhinosinusitis with nasal polyposis (CRSwNP), using the Sino-Nasal Outcome Test 22 items (SNOT-22). Methods This is a prospective, descriptive, and monocentric study involving all the patients who underwent surgery for CRS with nasal polyposis at Bejaia University Hospital over a period of 36 months, from January 1st, 2017, to December 31st, 2019. A SNOT-22 test was completed item by item with our patients, before any surgery, and after endoscopic sinus surgery at 1 month, 3 months, 6 months, 9 months, and 12 months. Results Sixty-five patients, having undergone ESS for CRS with nasal polyposis, were followed during a period 12 months. The average age of our patients was 42.06 ± 12.47 years, with 41.5% females and 58.5% males. Clinical examination showed that impairment was bilateral in 100% of our patients, while the nasal endoscopy showed that the polyps reached stage III in 87.7% of the cases on the right and 80% on the left. The mean Lund-Mackay CT score was 18.71 ± 4.77/24. All of the patients were treated with local and general short courses of corticosteroid therapy before ESS was indicated. Our results showed improvement in the QoL of our patients and maintenance of this gain after surgery. The average total SNOT-22 score for them was 49.41 ± 17.12 pre-operatively; post-operatively it was 12.14 ± 10.22 after 1 month; 10.31 ± 8.17 after 3 months; 9.35 ± 8.93 after 6 months; 12.21 ± 15.45 after 9 months and 12.63 ± 16.23 after 12 months. Conclusion ESS is the gold standard in the treatment of chronic rhinosinusitis with nasal polyposis after failure of medical therapy. The use of SNOT-22 test enabled us to confirm that whatever the surgical procedure applied, the QoL improves after surgery.
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