Salman R Punekar, Theodore Welling, J Randolph Hecht, Julian Molina, Caleb Smith, Edward Garon, M Pia Morelli, Marwan Fakih, Kedar Kirtane, Patrick M Grierson, Sandip P Patel, Yi Lin, Scott Kopetz, Frederick L Locke, Jeffrey Ward, Ariane Lozac’hmeur, Matthew Frigault, Sarah Nikiforow, Wen-Kai Weng, Jennifer Specht, Tomislav Dragovich, Judy Vong, Armen Mardiros, Kirstin Liechty, William Y Go, John Welch, Eric W Ng, Marcela Maus, David Maloney, Diane M Simeone
{"title":"634 EVEREST-1: CEA逻辑门控Tmod CAR - t细胞疗法(A2B530)在CEA表达相关的实体瘤患者中同时表现出HLA杂合性缺失(LOH)的无缝1/2期研究","authors":"Salman R Punekar, Theodore Welling, J Randolph Hecht, Julian Molina, Caleb Smith, Edward Garon, M Pia Morelli, Marwan Fakih, Kedar Kirtane, Patrick M Grierson, Sandip P Patel, Yi Lin, Scott Kopetz, Frederick L Locke, Jeffrey Ward, Ariane Lozac’hmeur, Matthew Frigault, Sarah Nikiforow, Wen-Kai Weng, Jennifer Specht, Tomislav Dragovich, Judy Vong, Armen Mardiros, Kirstin Liechty, William Y Go, John Welch, Eric W Ng, Marcela Maus, David Maloney, Diane M Simeone","doi":"10.1136/jitc-2023-sitc2023.0634","DOIUrl":null,"url":null,"abstract":"","PeriodicalId":500964,"journal":{"name":"Regular and Young Investigator Award Abstracts","volume":"4 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"634 EVEREST-1: A seamless phase 1/2 study of CEA logic-gated Tmod CAR T-cell therapy (A2B530) in patients with solid tumors associated with CEA expression also exhibiting HLA loss of heterozygosity (LOH)\",\"authors\":\"Salman R Punekar, Theodore Welling, J Randolph Hecht, Julian Molina, Caleb Smith, Edward Garon, M Pia Morelli, Marwan Fakih, Kedar Kirtane, Patrick M Grierson, Sandip P Patel, Yi Lin, Scott Kopetz, Frederick L Locke, Jeffrey Ward, Ariane Lozac’hmeur, Matthew Frigault, Sarah Nikiforow, Wen-Kai Weng, Jennifer Specht, Tomislav Dragovich, Judy Vong, Armen Mardiros, Kirstin Liechty, William Y Go, John Welch, Eric W Ng, Marcela Maus, David Maloney, Diane M Simeone\",\"doi\":\"10.1136/jitc-2023-sitc2023.0634\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\",\"PeriodicalId\":500964,\"journal\":{\"name\":\"Regular and Young Investigator Award Abstracts\",\"volume\":\"4 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Regular and Young Investigator Award Abstracts\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1136/jitc-2023-sitc2023.0634\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Regular and Young Investigator Award Abstracts","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1136/jitc-2023-sitc2023.0634","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
634 EVEREST-1: A seamless phase 1/2 study of CEA logic-gated Tmod CAR T-cell therapy (A2B530) in patients with solid tumors associated with CEA expression also exhibiting HLA loss of heterozygosity (LOH)