1223非病毒靶向敲入KRAS G12D特异性TCR、CD8αβ和traclocus中的嵌合细胞因子受体优于基于慢病毒的T细胞工程

Santosh Narayan, Allison P Drain, Nathaniel Swanson, Nicholas Rouillard, Tyler Warner, Nicole Danek, Ken Gareau, Cheryl Black, James Parsons, Anthony Thomas, Jinsheng Liang, Luhua Shen, Tanya Tetrault, Vince Nguyen, Iqraa Priyata, Sarah Vidyasagar, Joshua Francis, Xingyue He, Patrick J Browne, Rebecca C Lamothe, Meghan D Storlie, Gregory J Cost, Thomas M Schmitt, Philip D Greenberg, Smita S Chandran, Christopher A Klebanoff, Ankit Gupta, Damien Hallet, Gary Shapiro, Kim Nguyen, Loic Vincent
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1223 Non-viral targeted knock-in of a KRAS G12D specific TCR, CD8αβ, and chimeric cytokine receptor in theTRAClocus outperforms lentiviral-based engineering of T cells
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