唑来膦酸联合羟氯喹治疗SAPHO综合征1例

Q3 Medicine

Revmatologiia (Bulgaria) Pub Date : 2023-09-06 DOI:10.35465/31.2.2023.pp58-66

Sevdalina Lambova, G. Hadzhigeorgiev, G. Gelov, P. Uchilov

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引用次数: 0

摘要

摘要SAPHO综合征以一系列症状为特征，包括皮肤病变、无菌性骨炎(胸壁或其他骨骼部位)、周围滑膜炎等骨关节表现。由于缺乏随机临床试验和低患病率，SAPHO综合征没有既定的治疗指南。在此，我们报告一例SAPHO综合征合并胸骨炎和掌足底脓疱病，经唑来膦酸和羟氯喹成功治疗。

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A case of SAPHO syndrome treated with zoledronic acid and hydroxychloroquine

Abstract: SAPHO syndrome is characterized with a set of symptoms including skin lesions, osteoarticular manifestations like aseptic osteitis (of the anterior chest wall or other skeletal sites), peripheral synovitis. Due to the lack of randomized clinical trials and low prevalence of the condition, there are no established treatment guidelines for SAPHO syndrome. Here, we report a clinical case of SAPHO syndrome with osteitis of the sternum and palmoplantar pustulosis successfully treated with zoledronic acid and hydroxychloroquine.

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来源期刊

Revmatologiia (Bulgaria) Medicine-Rheumatology

CiteScore

0.30

自引率

0.00%

发文量