{"title":"作物保护剂下颌骨丙胺的合成","authors":"","doi":"10.56042/ijc.v62i9.3120","DOIUrl":null,"url":null,"abstract":"A simple synthesis of a novel fungicide Mandipropamid has been achieved in 6 steps, with an overall yield 43%. Synthesis started from commercially available starting materials, 4-chloroacetophenone and vanillin. The key steps involved in the synthesis are Cannizzaro and Henry reactions, amide bond formation and O-propargylation.","PeriodicalId":29765,"journal":{"name":"INDIAN JOURNAL OF CHEMISTRY","volume":"44 1","pages":"0"},"PeriodicalIF":0.4000,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Synthesis of Crop Protection Agent Mandipropamid\",\"authors\":\"\",\"doi\":\"10.56042/ijc.v62i9.3120\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A simple synthesis of a novel fungicide Mandipropamid has been achieved in 6 steps, with an overall yield 43%. Synthesis started from commercially available starting materials, 4-chloroacetophenone and vanillin. The key steps involved in the synthesis are Cannizzaro and Henry reactions, amide bond formation and O-propargylation.\",\"PeriodicalId\":29765,\"journal\":{\"name\":\"INDIAN JOURNAL OF CHEMISTRY\",\"volume\":\"44 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2023-09-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"INDIAN JOURNAL OF CHEMISTRY\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.56042/ijc.v62i9.3120\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"INDIAN JOURNAL OF CHEMISTRY","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.56042/ijc.v62i9.3120","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
A simple synthesis of a novel fungicide Mandipropamid has been achieved in 6 steps, with an overall yield 43%. Synthesis started from commercially available starting materials, 4-chloroacetophenone and vanillin. The key steps involved in the synthesis are Cannizzaro and Henry reactions, amide bond formation and O-propargylation.
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