氧化铈纳米颗粒的生物合成及其抗氧化活性

IF 0.2 Q4 Biochemistry, Genetics and Molecular Biology

Research Journal of Biotechnology Pub Date : 2023-08-15 DOI:10.25303/1809rjbt023028

Gopinath Mamatha Madhugiri, Sultana Sumreen, Manohar Punekar Shital, M.B. Nivedika, Tekupalli Ravikiran

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引用次数: 0

摘要

本研究旨在以苦参根提取物为原料，生物合成氧化铈纳米颗粒，并评价其抗氧化能力。在印度的阿育吠陀医学中，Withania somnifera被用作记忆增强剂，并用于治疗癌症和神经系统疾病。采用XRD、FTIR、UV-Vis、拉曼光谱、SEM-EDX和HR-TEM等表征技术证实了CeO2NPs的形成。表征结果表明，合成的纳米颗粒为球形，具有晶体性质，尺寸为10nm。通过OH自由基清除实验监测合成的CeO2NPs的抗氧化性能。532 nm处的最大吸光度由浅粉红色变为红橙色。CeO2NPs比维生素c具有明显的OH自由基清除活性。因此，我们的研究结果表明，生物源性CeO2NPs具有良好的抗氧化潜力，可能用于治疗氧化应激相关疾病。

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Biogenic synthesis of Cerium oxide nanoparticles and their antioxidant activity

The present study aimed to bio-synthesize cerium oxide nanoparticles from the root extract of Withania somnifera (Ashwagandha) and to evaluate their antioxidant potential. In Indian Ayurvedic medicine, Withania somnifera has been used as a memory booster and to treat cancer and neurological disorders. Several characterization techniques such as XRD, FTIR, UV-Vis, Raman spectroscopy, SEM-EDX and HR-TEM, were used to confirm the formation of CeO2NPs. The characterization results indicate that synthesized NPs were spherical with crystalline nature and size <10nm. An OH radical scavenging assay was done to monitor the antioxidant property of synthesized CeO2NPs. The maximum absorbance at 532 nm was measured by discoloration from light pinkish to reddish-orange. CeO2NPs exhibited significant OH radical scavenging activity than vitamin C. Therefore, our results suggest that biogenic CeO2NPs have shown good antioxidant potential and may be used to treat oxidative stress-related diseases.

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来源期刊

Research Journal of Biotechnology 工程技术-生物工程与应用微生物

CiteScore

0.60

自引率

0.00%

发文量

192

审稿时长

1.5 months

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