早期绝经和卵巢功能不全与痴呆风险增加相关:一项系统回顾和荟萃分析

Maturitas Pub Date : 2023-07-01 DOI:10.1016/j.maturitas.2023.04.177

Eleni Karamitrou, Panagiotis Anagnostis, Konstantina Vaitsi, Loukas Athanasiadis, Dimitrios Goulis

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引用次数: 0

摘要

背景/目的:由于雌激素具有神经保护作用，绝经期雌激素浓度的下降可能会损害绝经后妇女的认知功能。早期绝经(EM)是否与痴呆风险增加有关尚不清楚。本研究的目的是系统地回顾和荟萃分析关于EM或卵巢早衰(POI)与任何类型痴呆风险之间关系的现有证据。

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Early menopause and premature ovarian insufficiency are associated with increased risk of dementia: a systematic review and meta-analysis

Background / Aims: As estrogens play a neuroprotective role, the decline in their concentrations during menopause may compromise cognitive function in postmenopausal women. Whether early menopause (EM) is associated with an increased risk of dementia remains unclear. The purpose of this study was to systematically review and meta-analyze current evidence regarding the association between EM or premature ovarian insufficiency (POI) and the risk of dementia of any type.

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Maturitas

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