宫颈HPV与女性生育能力的关系

Alper İleri, İbrahim Karaca, Suna Yıldırım Karaca, Hande İleri, Can Ata, Pınar Tuğçe Özer, Ahmet Demir
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摘要

目的:生殖器人乳头瘤病毒(HPV)感染是世界范围内最常见的性传播病毒感染,在育龄女性人群中患病率为10-12%;很少有研究涉及HPV感染对生育能力的影响。本研究的目的是调查不孕妇女中HPV感染的存在。& # x0D;材料和方法:在本回顾性横断面研究中;评估2020年7月至2023年1月期间的不孕不育门诊记录。不孕症检查和评估按照指南进行。对不孕女性个体和对照组的HPV检测结果进行分析。 & # x0D;结果:共纳入234例不孕症妇女和340例非不孕症妇女,HPV阳性检出率为11.5%。与HPV无显著相关性(p=0.850)。 & # x0D;结论:HPV与女性不孕无显著相关性。HPV仍可能在不同基因型的不孕症中发挥作用。进一步的研究应包括HPV基因型。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The association between cervical HPV and female fertility
Objective: Genital human papillomavirus (HPV) infection is the most common sexually transmitted viral infection worldwide with a prevalence of 10-12% in the female population in the reproductive age; few studies addressed the effect of HPV infection on fertility. It is aimed to investigate the presence of HPV infection in infertile women in the present study. Materials and methods: In this retrospective cross-sectional study; the outpatient infertility clinic records between July 2020 and January 2023, were evaluated. Infertility examination and evaluation were performed following the guidelines. Infertile female individuals and control group’s HPV results were analyzed. Results: 234 infertile and 340 non-infertile females were included in the study, HPV positivity was found %11.5 for all infertile women. No significant relationship was found between and HPV (p=0.850). Conclusion: No significant association was found between female infertility and HPV. Still HPV may play a role in infertility with different genotypes. Further studies should include HPV genotypes.
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