菠萝蛋白酶在伤口愈合中的潜在作用综述

IF 0.4 Q4 ENGINEERING, MULTIDISCIPLINARY

International Journal of Integrated Engineering Pub Date : 2023-08-28 DOI:10.30880/ijie.2023.15.04.001

Celine Ng, Mohd Syahir Anwar Hamzah, Nadirul Hasraf Mat Nayan

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引用次数: 0

摘要

菠萝蛋白酶是从菠萝植物(Ananas comosus)中提取的蛋白水解酶。菠萝蛋白酶可以从菠萝茎和果实中提取。此外，它还可以从菠萝的废料中提取，如菠萝核、菠萝冠和菠萝皮。为了生产高质量的菠萝蛋白酶，各种提取和纯化方法，如反胶束系统、水两相系统、色谱技术和膜过滤技术已被使用。菠萝蛋白酶自1876年以来一直用于临床，并于1957年首次作为治疗剂引入。菠萝蛋白酶作为一种植物治疗药物，由于其安全性和缺乏不良副作用，已获得越来越多患者的接受和依从性。菠萝蛋白酶被认为是一种促进伤口愈合的营养物质，因为它含有几种密切相关的蛋白酶，具有抗炎、纤溶和清创的特性。

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Potential Role of Bromelain in Wound Healing Application: A Review

Bromelain is a proteolytic enzyme derived from the pineapple plant (Ananas comosus). Bromelain can be extracted from pineapple stems and fruits. Additionally, it can be derived from pineapple wastes such as the core, crown, and peel. Various extraction and purification methods such as reverse micellar system, aqueous two-phase system, chromatographic techniques, and membrane filtration have been used in order to produce high-qualitybromelain. Bromelain has been used clinically since 1876 and was first introduced as a therapeutic agent in 1957. Bromelain has gained increasing acceptance and compliance among patients as a phytotherapeutic drug due to its safety and lack of undesirable side effects. Bromelain is regarded as a nutrient that promotes wound healing due to the presence of several closely related proteinases that exhibit anti-inflammatory, fibrinolytic, and debridement properties.

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来源期刊

International Journal of Integrated Engineering ENGINEERING, MULTIDISCIPLINARY-

CiteScore

1.40

自引率

0.00%

发文量

期刊介绍： The International Journal of Integrated Engineering (IJIE) is a single blind peer reviewed journal which publishes 3 times a year since 2009. The journal is dedicated to various issues focusing on 3 different fields which are:- Civil and Environmental Engineering. Original contributions for civil and environmental engineering related practices will be publishing under this category and as the nucleus of the journal contents. The journal publishes a wide range of research and application papers which describe laboratory and numerical investigations or report on full scale projects. Electrical and Electronic Engineering. It stands as a international medium for the publication of original papers concerned with the electrical and electronic engineering. The journal aims to present to the international community important results of work in this field, whether in the form of research, development, application or design. Mechanical, Materials and Manufacturing Engineering. It is a platform for the publication and dissemination of original work which contributes to the understanding of the main disciplines underpinning the mechanical, materials and manufacturing engineering. Original contributions giving insight into engineering practices related to mechanical, materials and manufacturing engineering form the core of the journal contents.