孕期大麻使用:医院政策对毒理学筛查实践的影响[j]

Florence DiBiase, Erin Brousseau, Lindsey Pileika, Neha Reddy
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引用次数: 0

摘要

导言:缺乏妊娠毒理学筛查指南。研究表明,提供者在实施过程中存在偏见,并可能对患者造成严重后果。我们研究了一项医院新政策的效果。方法:一项协议概述口头筛选,咨询和毒理学筛选由医院工作组在怀孕期间使用大麻。已获得机构审查委员会的批准进行研究。回顾性图表回顾和分析住院低风险和母胎医学诊所政策实施前后6个月入院分娩的做法。结果:研究期间有2373例分娩,129对母婴进行了毒理学筛查。产妇筛查率在政策实施前后没有显著差异(2.6%对3.4%,P = 0.23)。在筛查的人群中,孕妇大麻素阳性的比例在政策出台后显著增加(13.8-42.9%,P = 0.005)。同样,新生儿筛查率在政策实施前后没有显著差异(3.4%对3.6%,P =.88),而新生儿大麻素阳性率在政策实施后显著增加(7.7-31.8%,P =.005)。在政策实施前和政策实施后进行筛查的人群在人口统计学上没有显著差异。结论:实施医院政策并没有改变筛查率或人口统计数据,但确实与大麻素检出率的增加有关。该政策的影响应慎重考虑。标准化口头筛查和风险讨论的好处是显而易见的,但毒理学筛查的潜在危害仍然存在。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cannabis Use in Pregnancy: Effects of a Hospital Policy on Toxicology Screening Practices [ID: 1377573]
INTRODUCTION: Guidelines for toxicology screening in pregnancy are lacking. Studies suggest provider bias in implementation and potential serious consequences for patients. We examined the effect of a novel hospital policy. METHODS: A protocol was outlined for verbal screening, counseling, and toxicology screening by a hospital task force on cannabis use in pregnancy. Institutional review board approval was obtained for study. A retrospective chart review and analysis of practices on admission for delivery was performed 6 months pre- and post-policy implementation in resident low-risk and maternal–fetal medicine clinics. RESULTS: There were 2,373 deliveries during the study period and 129 mother–infant dyads underwent toxicology screening. The rate of maternal screening did not significantly differ pre- and post-policy implementation (2.6% versus 3.4%, P =.23). In those screened, the rate of maternal cannabinoid positivity increased significantly post-policy (13.8–42.9%, P =.005). Similarly, the rate of neonatal screening did not significantly differ pre- and post-policy implementation (3.4% versus 3.6%, P =.88), while the neonatal cannabinoid positivity rate increased significantly post-policy (7.7–31.8%, P =.005). There were no significant differences in demographics of those screened pre- versus post-policy. CONCLUSION: Implementing a hospital policy did not change the rate or demographics of screening but did correlate with an increased cannabinoid detection rate. The effects of the policy should be cautiously considered. The benefit of standardized verbal screening and discussion of risks is clear, but potential harm from toxicology screening remains.
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