肺癌在低分辨率图像中的检测

Mostafa K .abd alrahman aladamey, Duha D .salman
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引用次数: 0

摘要

对所有肺癌患者来说,最重要的预后因素之一是准确检测转移灶。我们都知道,病理学家检查身体及其组织。在现有的临床方法上,它们具有繁琐和手工的任务。最近的分析受到了这些方面的启发。深度学习(DL)算法已被用于识别肺癌。开发的尖端技术在病理图像中的癌症识别和定位方面击败了病理学家。然而,这些技术在医学上是不可行的,因为它们需要大量的时间或计算能力来感知高分辨率图像。图像处理技术主要用于肺癌的预测和早期识别和治疗,以避免肺癌的发生。本研究旨在利用深度学习算法和低分辨率图像评估肺癌诊断。目标是看看是否可以创建机器学习(ML)模型,通过比较低分辨率和高分辨率图像来消耗部分资源,从而产生更高的置信度结论。通过压缩高分辨率图像,将深度学习管道构建到足够小的尺寸,然后将其输入CNN(卷积神经网络)之前进行二进制分类,即癌症或正常。为了提高整体性能,已经进行了许多增强,提供了数据增强,包括增强训练数据和实现组织检测。最后,创建的低分辨率模型实际上无法处理极低分辨率的输入,即299 x 299到2048 x 2048像素。考虑到缺乏分类能力,大幅减少模型的可预测时间只是一个边际效益。由于该方法有一个明显的缺陷,这是一个令人沮丧但却可以预见的发现:非常低的分辨率,基本上是在幻灯片上展开,只保留了关于宏观细胞结构的数据,这通常不足以单独诊断癌症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
LUNG CANCER DETECTION IN LOW-RESOLUTION IMAGES
One of the most important prognostic factors for all lung cancer patients is the accurate detection of metastases. Pathologists, as we all know, examine the body and its tissues. On the existing clinical method, they have a tedious and manual task. Recent analysis has been inspired by these aspects. Deep Learning (DL) algorithms have been used to identify lung cancer. The developed cutting-edge technologies beat pathologists in terms of cancer identification and localization inside pathology images. These technologies, though, are not medically feasible because they need a massive amount of time or computing capabilities to perceive high-resolution images. Image processing techniques are primarily employed for lung cancer prediction and early identification and therapy to avoid lung cancer. This research aimed to assess lung cancer diagnosis by employing DL algorithms and low-resolution images. The goal would be to see if Machine Learning (ML) models might be created that generate higher confidence conclusions while consuming fractional resources by comparing low and high-resolution images. A DL pipeline has been built to a small enough size from compressing high-resolution images to be fed into an or before CNN (Convolutional Neural Network) for binary classification i.e. cancer or normal. Numerous enhancements have been done to increase overall performance, providing data augmentations, including augmenting training data and implementing tissue detection. Finally, the created low-resolution models are practically incapable of handling extremely low-resolution inputs i.e. 299 x 299 to 2048 x 2048 pixels. Considering the lack of classification ability, a substantial reduction in models’ predictable times is only a marginal benefit. Due to an obvious drawback with the methodology, this is disheartening but predicted finding: very low resolutions, essentially expanding out on a slide, preserve only data about macro-cellular structures, which is usually insufficient to diagnose cancer by itself.
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