伊朗两例新生儿多系统炎症综合征与COVID-19暴露相关

Q3 Medicine

Journal of Comprehensive Pediatrics Pub Date : 2023-04-11 DOI:10.5812/compreped-134897

Maryam Saeedi, Kayvan Mirnia, Razieh Sangsari, Zeynab Jannatmakan, Vahid Ziaee

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引用次数: 0

摘要

导语:暴露于冠状病毒病-2019 (COVID-19)后会发生免疫失调，并影响许多器官。确诊为COVID-19检测呈阳性、发热、2个或2个以上器官受累，但在新生儿中很难诊断。病例介绍:在伊朗德黑兰儿童医学中心的新生儿重症监护室或新生儿病房中，有2名波斯新生儿患有败血症。两例患者的躯干和四肢均出现黄斑疹。两例患者的COVID-19检测结果均为阴性，但她们的母亲在分娩前都感染了COVID-19。在这两种情况下，全身和黄斑皮疹对皮质类固醇有反应。结论:新生儿黄斑疹可表现为多系统炎性疾病。父母或亲属中有COVID-19阳性病史的新生儿应考虑为本综合征。

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Neonatal Multisystem Inflammatory Syndrome Associated with COVID-19 Exposure in Two Cases from Iran

Introduction: Immune dysregulation happens after exposure to corona virus disease-2019 (COVID-19) and affects many organs. It is confirmed with a positive COVID-19 test history, fever, and the involvement of 2 or more organs, but it is hard to diagnose in neonates. Case Presentation: There were 2 Persian neonates admitted to the Neonatal Intensive Care Unit or neonatal ward of the Children’s Medical Center, Tehran, Iran, with sepsis in this case presentation. The trunk and extremities were affected by macular rashes in both cases. COVID-19 tests in both cases were negative, but both of their mothers were affected by COVID-19 before delivery. In both cases, systemic and macular rashes responded to corticosteroids. Conclusions: Macular rash can present multisystem inflammatory disease in neonates. Neonates with a positive history of COVID-19 in parents or relatives should be considered for this syndrome.

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来源期刊

Journal of Comprehensive Pediatrics Medicine-Pediatrics, Perinatology and Child Health

CiteScore

0.90

自引率

0.00%

发文量

期刊介绍： Journal of Comprehensive Pediatrics is the official publication of Iranian Society of Pediatrics (ISP) and a peer-reviewed medical journal which is published quarterly. It is informative for all practicing pediatrics including general medical profession.