[枯草热患者疾病特异性和非特异性季节性参数变化]。

Allergie und Immunologie Pub Date : 1990-01-01
H U Simon, G Metzner, E Keil, C Piesch, G Schlenvoigt, H Storz, L Jäger
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引用次数: 0

摘要

在BCH-069的i期试验中,10名患者接受了安慰剂皮下注射治疗,每周3次,持续4周。在季节前、季节和季节后不同时间观察免疫、血液学和生化指标。——报道了一些由季节性炎症引起的新观察结果。例如,c反应蛋白和甘油三酯水平都有明显增加。这些参数可能对未来花粉热抗过敏药物的试验有用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Disease-specific and non-specific seasonal parameter changes in hayfever patients].

10 patients have been treated by subcutaneous injections of placebo three times weekly for 4 weeks within a phase-I trial of BCH-069. Immunological, hematological and biochemical parameters were observed at different times: preseasonal, seasonal and postseasonal. --Some new observations are reported, which are induced by the seasonal inflammation. For example there was a strong increase of C-reactive protein and also an increase in the triglyceride level. --The parameters could be useful for trials of new antiallergic drugs in hay fever in the future.

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