68Ga-FAPi:心脏成像的途径和诊断

IF 0.6 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Current Cardiovascular Imaging Reports Pub Date : 2023-09-26 DOI:10.1007/s12410-023-09583-3

Cristina Elena Popescu, Paola Ferro, Irene Gotuzzo, Irene Burger, Axel Rominger, Federico Caobelli

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引用次数: 0

摘要

心肌纤维化是对心肌损伤的一种反应，在心室重构中起着关键作用。不同的纤维化模式与不同的疾病状态相关，但纤维化的存在和数量对预后的影响不同。近年来，成纤维细胞活化蛋白抑制剂(FAPi)正电子发射断层扫描(PET)因其在检测心肌纤维化、区分活动性和慢性疾病以及评估疾病进展和对治疗的反应方面的潜力而受到关注。我们旨在强调FAPi PET/CT在心血管成像中的最新应用，重点介绍其应用、优势、局限性，并强调未来的临床前景。

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68Ga-FAPi: Pathways and Diagnosis in Cardiac Imaging

Abstract Purpose of Review Myocardial fibrosis is a response to myocardial injury and plays a pivotal role in ventricular remodeling. Different patterns of fibrosis are associated with different disease states, but the presence and amount of fibrosis provide a different impact on prognosis. Recent Findings In the latest years, fibroblast activation protein inhibitor (FAPi) positron emission tomography (PET) gain interest for its potential in detecting myocardial fibrosis, in differentiating between active and chronic disease, and in the assessment of disease progression and response to treatment. Summary We aim to highlight the most relevant current applications of FAPi PET/CT in cardiovascular imaging, focusing on its applications, advantages, limitations, and to underline future clinical perspective.

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来源期刊

Current Cardiovascular Imaging Reports RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

2.20

自引率

0.00%

发文量

期刊介绍： Cardiovascular imaging technologies now play an expanded role in clinical practice. Beyond the diagnosis of a disease process, these techniques are rapidly transitioning to help guide therapy. The journal aims to keep readers current with rapidly evolving advances in instrumentation and imaging procedures that support the expanded role of these technologies in clinical practice. The journal intends to place the entire area of cardiovascular imaging in its proper prospective by establishing the indications and limitations of each imaging technique and by summarizing recent clinical advances. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas across the field, including cardiac magnetic resonance, nuclear imaging, echocardiography, cardiac computed tomography, intravascular, molecular, and hybrid imaging. Section Editors select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An Editorial Board of internationally diverse members ensures that topics include emerging research and suggests topics of special interest to their country/region. We also provide commentaries from well-known figures in the field.