肺癌筛查实施的叙述性回顾:增加循证实践的利用

James A. Miller, Robert M. Van Haren
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引用次数: 0

摘要

癌症是美国第二大死亡原因,肺癌每年导致的癌症死亡人数超过任何其他主要癌症。高死亡率的部分原因是在疾病早期缺乏症状。因此,导致诊断延误,直到肺癌发展到晚期,这时存在的潜在治疗选择即使有也更少。低剂量计算机断层扫描(LDCT)用于筛查高危患者已被发现在早期阶段识别肺癌,这与治疗干预的增加和肺癌死亡率的降低相对应。尽管肺癌筛查的危害风险相对较低,但仍未得到充分利用。接受肺癌筛查的合格患者的比例因地区而异,筛查率从不到合格患者的4%到某些州的18%不等。尽管国家和国际组织建议进行肺癌筛查,但这种低筛查率在过去几年中一直持续存在。提高利用率需要确定筛查的障碍和解决这些障碍的战略。随着筛查使用率的提高,预计肺癌的早期诊断率和死亡率也会随之持续改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A narrative review of lung cancer screening implementation: increasing utilization of evidence-based practice
: Cancer is the second leading cause of death in the United States, with lung cancer causing more cancer deaths annually than any other primary site. The high mortality is, in part, due to the lack of symptoms during early stage disease. There is therefore a resultant delay in diagnosis until lung cancer has progressed to later stages, when fewer if any potentially curative options exist. Low-dose computed tomography (LDCT) scanning for screening of high-risk patients has been found to identify lung cancer at earlier stages, and this has corresponded both with an increase in curative intervention and a decrease in lung cancer mortality. Although lung cancer screening carries a relatively low risk of harm, it remains underutilized. The rates of eligible patients that undergo lung cancer screening varies regionally, with rates of screening ranging from less than 4% of eligible patients up to 18% in some states. This low rate of screening has persisted over the past few years despite recommendations for lung cancer screening from national and international organizations. Improving utilization rates requires identification of barriers to screening and strategies to resolve these barriers. As screening utilization rates increase, continued improvement in rates of early diagnosis and mortality from lung cancer would then be expected to follow.
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