1例27岁男性肺炎后并发症气胸病例分析

Vince Thomas, Meraj Alam, Zohaer Muttalib, Nalin Ranasinghe, Leonard Ranasinghe
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引用次数: 0

摘要

自发性气胸是一种潜在的危及生命的疾病,当空气进入胸膜间隙导致胸膜之间的负压降低时,就会发生气胸,而不会发生创伤或损伤。自发性气胸是SARS-COV-2引起的严重急性呼吸综合征的不良并发症。人们认为自发性气胸可能是肺组织内弹性纤维破裂的结果。这种分解被认为是由人体自身的免疫反应引起的,特别是先天淋巴样细胞(ILCs),在对细胞内病原体(如病毒)的反应中,先天淋巴样细胞(ILCs)被证明会升高,但需要进一步的研究来明确SARS-CoV-2与免疫介导的气胸形成之间的因果关系。有限的研究着眼于气胸的病理生理学与COVID-19之间的联系,这就是为什么这个病例的患者感兴趣的原因。我们报告了一个独特的病例,一名27岁的男性向急诊科提出呼吸困难、胸痛和疲劳,他之前的COVID-19检测呈阳性。胸片诊断为气胸。在本报告中,我们讨论了与气胸相关的病理生理学、影像学和治疗及其与COVID-19的关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Case Study of Pneumothorax in a 27-year-old Male as a Possible Post- COVID 19 Infection Complication
Spontaneous Pneumothorax is a potentially life-threatening condition that is brought on when air makes its way into the pleural spaces resulting in decreased negative pressure between the pleural membranes without trauma or injury occurring. Spontaneous pneumothorax was reported as an adverse complication of severe acute respiratory syndrome brought on by SARS-COV-2. It is thought spontaneous pneumothorax may be a consequence of the breakdown of elastic fibers within the lung tissue. This breakdown is believed to be caused by the body’s own immune response in particular by innate lymphoid cells (ILCs) which have been shown to be elevated in response to intracellular pathogens like viruses, but additional research is needed to clearly state a causal relationship between SARS-CoV-2 and the immune-mediated formation of pneumothorax. Limited studies look at the link between the pathophysiology of Pneumothorax and COVID-19, which is why the patient from this case is of interest. We present a unique case of a 27-year-old male presenting to the Emergency Department complaining of difficulty breathing, chest pain, and fatigue who had prior tested positive for COVID-19. A diagnosis of pneumothorax was made by chest x-ray. In this report, we discuss the pathophysiology, imaging, and management related to pneumothorax and its connection to COVID-19.
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