等离子体喷射方案合成核壳纳米粒子(Cu: Se)治疗寄生虫利什曼病

Q3 Physics and Astronomy
Doaa Rifaat jassim, Ramiz Ahmed Al-ansari, Ban.H Adil
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引用次数: 0

摘要

为了治疗寄生虫利什曼病,采用常压冷等离子体制备了Cu:Se核壳纳米材料。在这项调查中,利什曼原虫治疗进行了实验研究(L. tropica)。具体而言,采用直径1mm的高压电极产生常压非热等离子体。以水溶液中的铜和硒盐为前驱体制备了铜硒纳米粒子。分别用x射线衍射、紫外光谱和FESEM对纳米颗粒进行了检测。理想的浓度(3:7)产生直径为17 nm的晶粒。用FESEM分析了Cu:Se纳米粒子的形貌。观察结果表明,合成的NPs呈球状(簇状)。直径为15-50 nm。因此,利用上述直径,用于治疗寄生虫利什曼病的纳米颗粒被创造出来。暴露48 h后,摩尔浓度为3:7、铜盐暴露30 min和硒盐暴露10 min时,寄生虫的热带乳杆菌百分比为78.8%。根据研究结果,这种核壳纳米粒子是治疗威胁全世界人类的寄生虫利什曼病的一种可行方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Synthesis core-shell nanoparticles (Cu: Se) by plasma jet scheme for parasitic leishmaniasis treatment
Cu:Se core shell nanomaterials were created using atmospheric cold plasma in order to treat parasite leishmaniasis. In this investigation, leishmania parasite treatment was examined experimentally (L. tropica). Specifically, a 1mm diameter high-voltage electrode was used to produce atmospheric pressure non-thermal plasma. Cu:Se NPs were made using copper and selenium salts in aqueous solution as a precursor. The nanoparticles were examined using X-ray diffraction ,UV spectroscopy and FESEM, respectively. The ideal concentration (3:7) yields grains with a diameter of 17 nm . Morphology of the Cu:Se NPs were carried out using FESEM. Observations show that the NPs synthesized were spherical(Cluster) in shape. with diameters of was 15-50 nm. Thus, utilizing the aforementioned diameter, nanoparticles for the treatment of parasitic leishmaniasis were created. After 48 hours of exposure, the percentage of L. tropica parasites for the parasites at a molar concentration of 3:7, 30 min of Cu salt exposure, and 10 min of Se salt exposure, was equal to 78.8%. The core-shell nanoparticles are a viable method for treating the parasite leishmaniasis that threatens people all over the world, according to the results.
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来源期刊
Plasma Medicine
Plasma Medicine Physics and Astronomy-Physics and Astronomy (all)
CiteScore
1.40
自引率
0.00%
发文量
14
期刊介绍: Technology has always played an important role in medicine and there are many journals today devoted to medical applications of ionizing radiation, lasers, ultrasound, magnetic resonance and others. Plasma technology is a relative newcomer to the field of medicine. Experimental work conducted at several major universities, research centers and companies around the world over the recent decade demonstrates that plasma can be used in variety of medical applications. It is already widely used surgeries and endoscopic procedures. It has been shown to control properties of cellular and tissue matrices, including biocompatibility of various substrates. Non-thermal plasma has been demonstrated to deactivate dangerous pathogens and to stop bleeding without damaging healthy tissue. It can be used to promote wound healing and to treat cancer. Understanding of various mechanisms by which plasma can interact with living systems, including effects of reactive oxygen species, reactive nitrogen species and charges, has begun to emerge recently. The aim of the Plasma Medicine journal will be to provide a forum where the above topics as well as topics closely related to them can be presented and discussed. Existing journals on plasma science and technology are aimed for audiences with primarily engineering and science background. The field of Plasma Medicine, on the other hand, is highly interdisciplinary. Some of prospective readers and contributors of the Plasma Medicine journal are expected to have background in medicine and biology. Others might be more familiar with plasma science. The goal of the proposed Plasma Medicine journal is to bridge the gap between audiences with such different backgrounds, without sacrificing the quality of the papers be their emphasis on medicine, biology or plasma science and technology.
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