希恩氏综合征1例报告

A. Reddy, A. Giri
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引用次数: 0

摘要

希恩综合征是指严重产后出血(PPH)后出现的垂体功能减退症。由于良好的产科护理,希恩氏综合征在发达国家已经成为一种罕见的疾病。在印度,这仍然是一个罕见而严重的问题。垂体坏死的严重程度决定了出现的时间,严重者立即出现,轻者在数年或数十年后出现。在她的早产双胎分娩时,一个年轻的妇女有先兆子痫,产前出血,产后出血。三年后继发性闭经。以虚弱、低血压、不耐寒、性毛脱落、乳房和外阴萎缩、性欲减退等症状确诊。ACTH、TSH、FSH、LH、催乳素、雌二醇、皮质醇和钠水平均较低,证实了诊断。用可的松、甲状腺素、雌激素和黄体酮进行激素替代治疗改善了她的一般情况。她的月经周期恢复了,生殖器官恢复了活力,性欲也恢复了。不太严重的希恩氏综合征发病隐匿,表现模糊,因此诊断不足。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Case Report on Sheehan’s Syndrome
Sheehan's Syndrome refers to hypopituitarism that develops after a severe postpartum haemorrhage (PPH).Sheehan's Syndrome has become a rare entity in developed countries due to good obstetric care. In the Indian context, it is still a rare and serious problem. The severity of the pituitary necrosis determines the timing of presentation, with severe cases presenting immediately and less severe cases presenting years or decades later. At the time of her premature twin pregnancy delivery, a young woman had preeclampsia, antepartum haemorrhage, and postpartum haemorrhage. She presented with secondary amenorrhoea three years later. The diagnosis was confirmed by symptoms such as weakness, hypotension, cold intolerance, loss of sexual hair, breast and vulval atrophy, and loss of libido. ACTH, TSH, FSH, LH, Prolactin, as well as Estradiol, Cortisol, and Sodium levels were all low, confirming the diagnosis. Hormone replacement therapy with Cortisone, Thyroxine, Estrogen and Progesterone improved her general condition. Her menstrual cycles have been restored, her genital organs have been rejuvenated, and her libido has been regained. Less severe forms of Sheehan’s syndrome are insidious in onset, vague in presentation and so are under diagnosed.
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