Transcranial magnetic simulation over posterior parietal cortex affects attentional function

Objective: The posterior parietal cortex (PPC) is involved in cognitive attentional activity, according to neuroimaging research. Its specific role in the brain network responsible for attention need to be further identified. Approach: In this study, an attention network test (ANT) was designed. 1-Hz low-frequency repeated transcranial magnetic stimulation (rTMS) was performed over the right PPC. Behavioral and EEG data were analyzed before and after stimulation. Main results: The behavioral results showed that the frontoparietal network was directly connected to spatial orientation and executive functions. Low-frequency TMS produced an inhibitory effect in opposition to the learning effect, which persisted 24 hours after stimulation and was most pronounced under spatial cues. Event-related potentials (ERP) results showed that the stimulation inhibited the posterior parietal brain neural activity, and in particular, had a significant inhibitory effect on spatial attention. Significance: PPC is crucial in attentional orienting and executive functions. Exploring ways to intervene in brain activity has significant implications for people to recover attentional function.