{"title":"用伽马闪烁成像测定生物陶瓷扩散特性的可行性","authors":"J. Smith, D. Reynolds, P. K. Bajpai, A. Sedaghat","doi":"10.1109/SBEC.1996.493157","DOIUrl":null,"url":null,"abstract":"This study investigated the feasibility of determining an apparent diffusion coefficient for diffusion of technetium-99m-labeled albumin (MICROLITE/sup R/) through ZCAP (Zinc-Calcium-Phosphorous Oxide) ceramics. Gamma scintigraphy was used for non-invasive observation of diffusion. Data analysis assumed a well-mixed solution, steady-state conditions over the measurement time interval, and passive diffusion as the primary mode of mass transport through the ceramic. Attenuation of 140 keV gamma rays was found to be significant in ZCAP ceramic. Although the data obtained was not adequate to calculate an apparent diffusion coefficient, such a determination appears feasible with modifications to the test protocol.","PeriodicalId":294120,"journal":{"name":"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference","volume":"57 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1996-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Feasibility of determining diffusion characteristics of bioceramics using gamma scintigraphy\",\"authors\":\"J. Smith, D. Reynolds, P. K. Bajpai, A. Sedaghat\",\"doi\":\"10.1109/SBEC.1996.493157\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This study investigated the feasibility of determining an apparent diffusion coefficient for diffusion of technetium-99m-labeled albumin (MICROLITE/sup R/) through ZCAP (Zinc-Calcium-Phosphorous Oxide) ceramics. Gamma scintigraphy was used for non-invasive observation of diffusion. Data analysis assumed a well-mixed solution, steady-state conditions over the measurement time interval, and passive diffusion as the primary mode of mass transport through the ceramic. Attenuation of 140 keV gamma rays was found to be significant in ZCAP ceramic. Although the data obtained was not adequate to calculate an apparent diffusion coefficient, such a determination appears feasible with modifications to the test protocol.\",\"PeriodicalId\":294120,\"journal\":{\"name\":\"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference\",\"volume\":\"57 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1996-03-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/SBEC.1996.493157\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/SBEC.1996.493157","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Feasibility of determining diffusion characteristics of bioceramics using gamma scintigraphy
This study investigated the feasibility of determining an apparent diffusion coefficient for diffusion of technetium-99m-labeled albumin (MICROLITE/sup R/) through ZCAP (Zinc-Calcium-Phosphorous Oxide) ceramics. Gamma scintigraphy was used for non-invasive observation of diffusion. Data analysis assumed a well-mixed solution, steady-state conditions over the measurement time interval, and passive diffusion as the primary mode of mass transport through the ceramic. Attenuation of 140 keV gamma rays was found to be significant in ZCAP ceramic. Although the data obtained was not adequate to calculate an apparent diffusion coefficient, such a determination appears feasible with modifications to the test protocol.
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