快速高光谱刺激拉曼散射显微镜定量分析药物片剂老化

Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN) Pub Date : 1900-01-01 DOI:10.1364/ntm.2023.ntu2c.5

Yuxiao Wei, I. Pence, Conor L. Evans

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引用次数: 0

摘要

固体制剂的药物开发需要测试均匀性和活性药物成分的稳定性。我们演示了快速化学成像通过外延探测稀疏光谱采样刺激拉曼散射来量化API和辅料的降解和分布。

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Quantitative analysis of drug tablet aging by fast hyperspectral stimulated Raman scattering microscopy

Pharmaceutical development of solid-state formulations requires testing for uniformity and active pharmaceutical ingredient stability. We demonstrate fast chemical imaging by epi-detected sparse spectral sampling stimulated Raman scattering to quantify API and excipient degradation and distribution.

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来源期刊

Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)

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