单细胞分析用微系统

2010 2nd Circuits and Systems for Medical and Environmental Applications Workshop (CASME) Pub Date : 2010-12-01 DOI:10.1109/CASME.2010.5706686

A. Han

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引用次数: 5

摘要

近年来，单细胞分析已成为一个备受关注的话题。任何细胞群都是异质的。然而，大多数传统的细胞分析只能捕获细胞群体的平均反应，单细胞分析允许测量和分析这种异质性，并能够识别和研究各种亚群体。微流控和芯片实验室技术非常适合这种分析，因为它们在操纵和分析微米级物体和精确控制其微环境方面具有独特的能力。这里介绍了两个用于单细胞分析的微流体装置的例子。

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Microsystems for single cell analysis

Single cell analysis has become a topic of great interest in recent years. Any population of cells is heterogeneous. Whereas most traditional cell analysis can capture only average responses from a population of cells, single cell analysis allows measuring and analyzing this heterogeneity and enables identifying and studying various sub-populations. Microfluidic and lab-on-a-chip technologies are ideally suited for such analysis due to their unique capabilities in manipulating and analyzing micrometer-scale objects and accurately controlling their microenvironments. Two such examples of microfluidic devices for single cell analysis are presented here.

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2010 2nd Circuits and Systems for Medical and Environmental Applications Workshop (CASME)

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