药物警戒-药物安全监测工具

Shivangi Chauhan
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引用次数: 2

摘要

这篇叙述性综述的目的是讨论药物安全、全球药理学权威及其责任、不良事件报告的过程以及药物警戒的主要功能。药物警戒是一门确保患者对市场上新推出和成熟的药品安全的科学。药物警戒被认为是一种用于观察和估计药物不良反应(adr)的特殊工具,对于成功的药物管理计划、临床试验和公共卫生计划至关重要。在过去的几年中,报告的adr数量有所增加,因此数据量也有所增加。处理如此庞大的数据和了解药物警戒的需求,需要高技能和熟练的人员立即发现药物的副作用,并保护产品不被不当移除。现有的全球药物警戒中心网络将通过与乌普萨拉监测中心协调的独立审查程序得到加强。它的主要作用是评估试验和药物安全的关键问题,这些问题可能会影响到国界以外的公共卫生。在这个全球性的舞台上,药物警戒成为临床研究的重要组成部分。大多数国家建立了药物警戒中心来监测药物安全;然而,千禧年药物警戒面临着改善安全性和药物监测的重大挑战。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pharmacovigilance- A drug safety monitoring tool
The objective of this narrative review is to converse about drug safety, global pharmacological authorities and their responsibility, the process of adverse event reporting, and the main functions of pharmacovigilance. Pharmacovigilance is a science that ensures patient safety against both newly launched and well-established medicinal products in the market. Pharmacovigilance is considered a specific tool used for observing and estimating Adverse Drug Reactions (ADRs) and is essential for successful drug management programs, clinical trials, and public health programs. In the few past years, the number of reported ADRs got increased as a result of which the volume of data got increased. To handle such huge data and the need to understand the pharmacovigilance, it requires highly skilled and proficient people for immediate detection of drug's side effects and protects the product from improper removal. The existing global network of pharmacovigilance centers will be strengthened through an independent review process in coordination with the Uppsala Monitoring Center. Its main role is to assess trials and crucial issues of drug safety that probably influence public health beyond national borders. In this global arena, Pharmacovigilance becomes an important and integral part of clinical research. Most of the countries set up pharmacovigilance centers to monitor drug safety; however, millennial pharmacovigilance faces major challenges for improved safety and drug monitoring.  
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