Rheumatoid arthritis

In this chapter, we will cover rheumatoid arthritis. First we will describe the epidemiology, aetiology, and pathogenesis of rheumatoid arthritis, followed by the histological changes in joints. Clinical features of the disease are described and how it affects the foot and ankle at disease onset and in the early stages. The disability and impact of the disease is considered prior to describing systemic treatment methods. Specific foot disease associated with rheumatoid arthritis is covered, split by area of the foot. Imaging requirements are outlined, including disease-specific considerations, and specific management options are discussed. Finally, clinical trials and the future direction of research are covered.