用图像型测量数据对扩散反应过程进行逆建模

A. Penenko, Z. Mukatova
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引用次数: 1

摘要

研究一维扩散反应模型的逆源问题。测量数据以相互作用物质子集的浓度场动力学图像的形式给出。这些逆问题出现在生长组织的研究(形态发生理论)、组织工程技术的发展以及现代数学生物学的其他领域。由独立伴随问题解的集合组成的灵敏度算子允许将反问题转化为一类非线性不适定积分方程。族的每一个成员对应于提取图像某些特征的图像到结构算子。用截断奇异值分解和迭代正则化相结合的newton - kantorovich型算法求解该类方程。由于采用了伴随问题集成的设计,该算法可以有效地并行化。在Brusselator模型的情况下,用数值说明了该算法的收敛性和稳定性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Inverse modeling of diffusion-reaction processes with image-type measurement data
The inverse source problem for 1D diffusion-reaction model is considered. The measurement data is given as the images of the concentration fields dynamics for the subset of the interacting species. These inverse problems arise in the study of the growing tissues (morphogenes theory), in the development of the tissue engineering technologies and in the other fields of modern mathematical biology. The sensitivity operator, composed of the ensemble of the independent adjoint problem solutions allow to transform the inverse problem to the family of nonlinear ill-posed integral equations. Each member of the family correspond to the image to structure operator that extracts certain features of the image. An equation from the family is solved with the Newton-Kantorovich-type algorithm combining truncated SVD and iterative regularization. Due to the design with the adjoint problems ensemble, the algorithm can be efficiently parallelized. The algorithm’s convergence and stability are illustrated numerically in Brusselator model case.
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