具有疫苗接种策略的分数阶COVID-19大流行的新建模和分析

Mehmet Yavuz, Fatma Özlem Coşar, F. Usta
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引用次数: 3

摘要

近年来,对新冠肺炎的数学建模和分析进行了许多说明性研究。由于疫苗接种过程的不确定性及其对疾病的有效性,目前还没有足够的研究。在这种情况下,本研究建立了一个数学模型,以揭示最近几家公司开发的疫苗治疗对COVID-19的影响。在该模型中,构建了包括易感人群、感染人群、暴露人群和恢复人群在内的五维常微分方程组。上述系统被考虑为分数阶,以调查和指出更详细的疾病分析及其未来预测。此外,除了解的正性、存在性和唯一性外,还提供了生物可行区域。计算基本繁殖数,即预期继发感染数,即易感人群中由这种感染引起的预期感染数。在数值模拟中,从文献中获取和估计的参数值被用来执行所提出的模型的解。在数值模拟中,采用了Adams-Bashforth算法,这是一种著名的数值格式。©2022美国物理学会。版权所有。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A novel modeling and analysis of fractional-order COVID-19 pandemic having a vaccination strategy
Recently, many illustrative studies have been performed on the mathematical modeling and analysis of COVID-19. Due to the uncertainty in the process of vaccination and its efficiency on the disease, there have not been taken enough studies into account yet. In this context, a mathematical model is developed to reveal the effects of vaccine treatment, which has been developed recently by several companies, on COVID-19 in this study. In the suggested model, as well as the vaccinated individuals, a five-dimensional ordinary differential equation system including the susceptible, infected, exposed and recovered population is constructed. This mentioned system is considered in the fractional order to investigate and point out more detailed analysis in the disease and its future prediction. Moreover, besides the positivity, existence and uniqueness of the solution, biologically feasible region are provided. The basic reproduction number, known as expected secondary infection which means that expected infection among the susceptible populations caused by this infection, is computed. In the numerical simulations, the parameter values taken from the literature and estimated are used to perform the solutions of the proposed model. In the numerical simulations, Adams-Bashforth algorithm which is a well-known numerical scheme is used to obtain the results. © 2022 American Institute of Physics Inc.. All rights reserved.
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