肺结核后并发肺毛霉病是一种新出现的危险因素:一个罕见的病例报告

Divya Khanduja, Naveen Pandhi
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摘要

肺毛霉病是一种罕见的肺部真菌疾病,常见于免疫功能低下的个体。它是由接合菌类真菌引起的。它是继曲霉病和念珠菌病之后的第三种最常见的侵袭性真菌感染。危险因素包括血液系统恶性肿瘤、糖尿病和免疫功能低下的患者。由于非特异性的临床表现和治疗延误而难以早期诊断,并伴有较高的死亡率。正如我们所知,结核病和艾滋病在印度这样的国家非常普遍。在印度等发展中国家,后肺结核正在成为肺毛霉菌病的一个危险因素。非溶解性肺炎患者常被误诊为肺结核。肺毛霉病的诊断是基于临床标本中真菌菌丝的表现。我们强调临床怀疑的重要性,在这些情况下,早期诊断和早期治疗的开始可以扭转发病率和死亡率与肺毛霉菌病。我们报告2例肺毛霉菌病出现在肺结核后患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pulmonary mucormycosis in post-pulmonary tuberculosis as an emerging risk factor: A rare case report
Pulmonary mucormycosis is an uncommon pulmonary fungal disease, which is commonly seen in immunocompromised individuals. It is caused by fungi of class Zygomycetes. It constitutes the third most common invasive fungal infection following aspergillosis and candidiasis. Risk factors include patients with hematological malignancies, diabetes mellitus, and immunocompromised states. It is difficult to diagnose early due to non-specific clinical presentation and delay in treatment associated with greater mortality. As we know that Tuberculosis and HIV are highly prevalent in country like India. Post pulmonary tuberculosis is emerging as a risk factor for Pulmonary mucormycosis in the developing countries like India. Patients with non-resolving pneumonia are generally misdiagnosed as Pulmonary tuberculosis. The diagnosis of Pulmonary Mucormycosis is based upon demonstration of fungal hyphae in the clinical specimen. We highlight the importance of clinical suspicion in these cases for early diagnosis and early treatment initiation can reverse morbidity and mortality associated with Pulmonary Mucormycosis. We report 2 cases of Pulmonary mucormycosis present in post-pulmonary tuberculosis patients.
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