一种处理数字基因表达谱的离散化方法

Jibin Qu, Jinxia Zhang, Chenyang Huang, Baogui Xie, Yong Wang, Xiang-Sun Zhang
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引用次数: 2

摘要

离散化是分析基因表达数据的重要预处理步骤,目前已经提出了许多算法。然而,大多数离散化方法都是针对微阵列设计的。数字基因表达谱作为一种新技术,克服了微阵列技术的局限性,具有广泛的应用前景。在本文中,我们提出了一种新的DGE数据离散化方法,并在时间序列基因表达数据集上验证了该方法的有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A novel discretization method for processing digital gene expression profiles
Discretization serves as an important preprocessing step for analyzing gene expression data and many algorithms have been proposed. However, most of the discretization methods were designed for microarrays. As a new technology, digital gene expression (DGE) profiles can overcome the limitation of microarrays and were applied in a widely range. In this paper, we proposed a novel discretization method for DGE data and the validations in a time-series gene expression dataset proved the efficiency of our method.
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