[高剂量结晶青霉素和普鲁卡因青霉素治疗神经梅毒的结果]。

IF 0.5 Q4 DERMATOLOGY

Przeglad dermatologiczny Pub Date : 1990-09-01

Z Starzycki, J Markiewicz, J Mayer, J Bogdaszewska-Czabanowska

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引用次数: 0

摘要

比较两组神经梅毒患者的治疗效果。23例患者静脉滴注结晶青霉素10天，每日剂量20 ~ 24兆U，联合probenecid。随后静脉滴注普鲁卡因青霉素，每日剂量1.2 μ U，总剂量12 ~ 50 μ U，平均随访7、8个月。第二组34例患者给予普鲁卡因青霉素静脉滴注，每日剂量为1.2兆U，总剂量为24 ~ 60兆U，平均随访2.5年。两组治疗结果差异无统计学意义。在3例早期无症状神经梅毒再感染患者中，尽管进行了青霉素强化治疗，但仍发生了血清和脑脊液耐药梅毒。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

[Results of the treatment of neurosyphilis with high doses of crystalline and procaine penicillins].

The results of the treatment in two groups of patients with neurosyphilis are compared. In 23 cases, i.v. infusions of crystalline penicillin were given for 10 days in daily dose of 20-24 mega U., combined with probenecid. Then it was followed by i.m. procaine penicillin in daily dose of 1.2 mega U., in total dose 12-50 mega U. The mean duration of follow-up was 7,8 months. The second group (34 cases) was treated with procaine penicillin i.m. in daily dose of 1.2 mega U., the total dose was 24-60 mega U. The mean duration of follow-up was 2.5 years. The differences between the results of the treatment in both groups were not significant. In 3 reinfected patients with early asymptomatic neurosyphilis in spite of intensive treatment with penicillin sero- and cerebro-spinal fluid-resistant syphilis developed.

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来源期刊

Przeglad dermatologiczny DERMATOLOGY-

CiteScore

0.80

自引率

14.30%

发文量

审稿时长

12 weeks

期刊介绍： Przegląd Dermatologiczny (ang. Dermatological Review) is a bimonthly magazine of the Polish Dermatological Association. It publishes original (clinical and experimental) papers, review papers, care reports, reports from congresses, reviews of books, announcements, letters to the editor and special papers (requested by the editors), concerning selected dermatological and interdisciplinary issues. Papers sent to the editor are reviewed.