[不同阶段类天疱疮患者皮肤的免疫病理学研究]。

IF 0.5 Q4 DERMATOLOGY

Przeglad dermatologiczny Pub Date : 1990-09-01

J D Torzecka, A Lutowiecka-Wranicz, A Sysa-Jedrzejowska, E Waszczykowska, B Dziankowska-Bartkowiak

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引用次数: 0

摘要

该研究的目的是证明在大疱性类天疱疮(BP)患者中，皮肤中免疫沉积物的存在与病理过程的活性之间是否存在相关性。我们调查了39例BP病史，时间从3个月到17年不等。采用直接免疫荧光法对不同疾病活动性进行多次重复调查。结果表明，皮肤中免疫沉积的消失与疾病的缓解之间存在着完全的相关性。此外，已有研究表明，补体比IgG部分消失得更早。这些结果表明抗基底区抗体，特别是补体在诱发BP病变中的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

[Immunopathological studies of the skin of patients with pemphigoid at different stages of the disease].

The aim of the investigation was to demonstrate whether there is a correlation, in patients with bullous pemphigoid (BP), between the presence of immune deposits in the skin and the activity of the pathological process. We investigated 39 cases with a BP anamnese dating from 3 months up to 17 years. We repeated the investigations several times by means of direct immunofluorescence method in different disease activity. It was demonstrated that there is a complete correlation between the disappearance of the immune deposits in the skin and the remission of the disease. Moreover, it has been shown, that the complement disappears earlier than IgG fraction. These results show the role of the antibasement zone antibodies and especially the complement in the inducement of BP lesions.

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来源期刊

Przeglad dermatologiczny DERMATOLOGY-

CiteScore

0.80

自引率

14.30%

发文量

审稿时长

12 weeks

期刊介绍： Przegląd Dermatologiczny (ang. Dermatological Review) is a bimonthly magazine of the Polish Dermatological Association. It publishes original (clinical and experimental) papers, review papers, care reports, reports from congresses, reviews of books, announcements, letters to the editor and special papers (requested by the editors), concerning selected dermatological and interdisciplinary issues. Papers sent to the editor are reviewed.