GenServ:基于可扩展节能加速器的基因组测序服务

Chao Wang, Haijie Fang, Shiming Lei, Lei Gong, Aili Wang, Xi Li, Xuehai Zhou
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引用次数: 2

摘要

字符串匹配作为一种传统的算法,随着基因测序技术的发展,海量数据的产生受到了挑战。调查表明,在基因测序过程中会出现大量的短读片段,迫切需要一种高效的测序方法。BWA是一种处理短读映射的有效算法。与其他短读映射算法相比,BWA算法具有较小的尺寸,但这并不影响其效果。然而,目前还没有一个系统专门用于加速BWA算法。因此,我们决定建立一个系统来加快算法的速度,并使其满足基因测序的应用。在本文中,我们提出了基因组测序服务的可扩展的节能加速器。特别地,我们首先介绍了BWA算法,并说明了选择该算法的原因。然后,我们实现了一个基于FPGA的加速器来提高算法的性能。通过与其他主要平台在算法加速方面的比较,讨论了FPGA平台的优点和其他平台的局限性。最后,我们利用Xilinx ZYNQ FPGA开发板搭建了硬件平台,结果表明我们的加速器在加速和资源利用率方面取得了良好的效果,并在功耗和成本之间取得了平衡。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
GenServ: Genome Sequencing Services on Scalable Energy Efficient Accelerators
As a traditional algorithm, the string match meets a challenge with the development of the massive volume of data be-cause of gene sequencing. Surveys show that there will be a huge amount of short read segments during the process of gene sequencing and the need for a highly efficient is urgent. The BWA is an effective algorithm to deal with the short read mapping. Compared with other short read mapping algorithms, the BWA algorithm has a smaller size, and this does not influence its effect. However, there is still not a system is used to accelerate the BWA algorithm especially. Thus we decide to build a system to expedite the algorithm and make it satisfied with the application of gene sequencing. In this paper, we present genome sequencing services on scalable energy-efficient accelerators. Especially, we first in-troduce the BWA algorithm and claim the reason for the choice of the algorithm. Then, we implement an accelerator based on FPGA to improve the performance of the algorithm. Com-pared to the other major platforms in accelerating the algo-rithm, we discuss the advantages of the FPGA platform and the limit of the other platform. Last, we build our hardware platform with a Xilinx ZYNQ FPGA development board, and the result shows that our accelerator can achieve a promising speedup and resource utilization and make it balanced be-tween power and cost.
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