Idiopathic peripheral lower-limb gangrene in infancy

Idiopathic peripheral lower-limb gangrene in infancy is a rare condition with attendant difficulty in making adequate or accurate diagnosis, as there are no clear-cut causes of the condition as the name suggests. The predisposing factors are important to consider as a guide for diagnosis and treatment, but timely intervention to restore the normal physiological status of the patient and reverse progression of ischemia is much more important. This is a presentation of two cases that were similarly managed for peripheral lower-limb idiopathic gangrene. Both cases were male infants. The conservative approach adopted in both cases yielded remarkable results.