人血清磷脂酶A2的测定。两种方法的比较。

Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie Pub Date : 1990-08-01

F Märki, W Pignat, B Steinbrückner, G E Hoffmann

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引用次数: 0

摘要

测定血清磷脂酶A的光度法与测定磷脂酶A2的特异性放射法进行了比较。这两种方法具有高度的相关性。炎症性和非胰腺坏死性疾病患者血清中磷脂酶A活性升高可归因于中性活性、钙敏感的磷脂酶A2，而不是胰腺磷脂酶A2。磷脂酶A1似乎对磷脂酶A的总体活性没有显著贡献。

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Determination of human serum phospholipase A2. Comparison of two methods.

A photometric assay for serum phospholipase A is compared with a radiometric assay specific for phospholipase A2. The methods show a high correlation. The increased phospholipase A activity in sera of patients with inflammatory and non-pancreatic necrotizing diseases is attributable to a neutral-active, calcium-sensitive phospholipase A2 but not to pancreatic phospholipase A2. Phospholipase A1 did not seem to contribute significantly to the overall activity of phospholipase A.

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Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie

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